Multipurpose biological applications of excitation-dependent fluorescent carbon nano dots emanated from biomass waste

被引:5
|
作者
Thangadurai, T. Daniel [1 ]
Manjubaashini, N. [2 ]
Sowndarya, A. [1 ]
Subitha, A. [1 ]
Kausalya, G. [1 ]
Shanmugaraju, S. [3 ]
Ahmad, I. [4 ]
Thomas, Sabu [5 ]
Kalarikkal, Nandakumar [5 ]
机构
[1] KPR Inst Engn & Technol, Ctr Res & Dev, Dept Chem, Coimbatore 641407, Tamilnadu, India
[2] Univ Madras, Natl Ctr Nanosci & Nanotechnol, Chennai 600025, Tamilnadu, India
[3] Indian Inst Technol, Dept Chem, Palakkad 678557, Kerala, India
[4] Univ Kebangsaan Malaysia, Fac Sci & Technol, Bangi 43600, Selangor, Malaysia
[5] Mahatma Gandhi Univ, Int & Interuniv Ctr Nanosci & Nontechnol, Kottayam 686650, Kerala, India
关键词
Rice husk; Biomass; CNDs; Cytotoxicity; Anti-inflammatory; Bioimaging; POT HYDROTHERMAL SYNTHESIS; GREEN SYNTHESIS; BIOCOMPATIBILITY; NANOPARTICLES; CYTOTOXICITY; TOXICITY; NITRITE; MORIN; PROBE; WATER;
D O I
10.1016/j.matchemphys.2023.128113
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Carbon Nanodots (CNDs) generated from biomass wastes have a wide range of biological functionalities and are used in a variety of applications. Especially, the biomedical applications shown by the CNDs derived from biomass waste materials received great attention from researchers around the globe. Herein we report the synthesis of CNDs from rice husk biomass waste using a hydrothermal method. XRD pattern demonstrates the amorphous nature of CNDs with hexagonal graphite structure. Microscopic images confirmed that as-synthesized CNDs are in spherical morphology with an average size of 25-30 nm and average interplanar spacing of 0.265 nm. XPS, Raman, and FTIR spectral analyses were performed to examine the presence of functional groups and defects in CNDs. Excitation-dependent emission properties of CNDs (CYRILLIC CAPITAL LETTER EFF 9.6%) were studied by UV-Vis., Contour, and fluorescence techniques. In response to the findings of the cytotoxicity experiment and the CNDs' strong emission, we carried out several biostudies to prove its importance. The CNDs possess outstanding cell viability (98%), excellent anti-inflammatory activity of 33% of LOX, 34% of COX, 45% of NO inhibition at 100 & mu;L, sig-nificant protein denaturation (62%; IC50 20.04 & mu;L/mL), and bright bioimaging on Zebrafish characteristics, which accentuate the perception of waste to wealth.
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页数:12
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