Generation of a human fibroblast-derived induced pluripotent stem cell line KRIBBi009-A from a patient with breast cancer

被引：0
|
作者：
Son, Naeun [1 ,2 ]
Son, Ye Seul [1 ]
Jung, Cho-Rok [1 ,2 ]
Son, Mi -Young [1 ,2 ]
机构：
[1] Korea Res Inst Biosci & Biotechnol KRIBB, Daejeon 34141, South Korea
[2] Korea Univ Sci & Technol, KRIBB Sch Biosci, Daejeon 34113, South Korea
来源：
STEM CELL RESEARCH | 2023年 / 68卷
基金：
新加坡国家研究基金会;
关键词：
D O I：
10.1016/j.scr.2023.103060
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Patient-derived human induced pluripotent stem cells (iPSCs) provide a potentially useful resource for studying disease pathology and therapeutics. In this study, we generated the breast cancer patient-derived KRIBBi009-A-iPSC line from normal fibroblasts using the Sendai virus, which expressed pluripotent markers and exhibited differentiation capacity across 3 germ layers through in vitro differentiation and in vivo teratoma assay. A normal karyotype and the absence of cross-contamination of the cell lines were confirmed. Consequently, the developed iPSC line has been confirmed to be suitable for use in various studies.
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页数：5
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