Ni-Catalyzed Stereoconvergent Reductive Dimerization of Bromocyclobutenes

被引：0
|
作者：
Spiess, Philipp [1 ]
Matheu, Sergio Armentia [1 ]
Bauer, Adriano [1 ]
Coussanes, Guilhem [1 ]
Shaaban, Saad [1 ]
Maulide, Nuno [1 ]
机构：
[1] Univ Vienna, Inst Organ Chem, A-1090 Vienna, Austria
来源：
ORGANIC LETTERS | 2023年 / 26卷 / 01期
基金：
欧洲研究理事会; 奥地利科学基金会;
关键词：
CROSS-COUPLING REACTIONS; STEREOSELECTIVE-SYNTHESIS; CYCLOBUTENE; REACTIVITY;
D O I：
10.1021/acs.orglett.3c03909
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A nickel-catalyzed reductive dimerization of bromocyclobutenes to produce unusual and unprecedented cyclobutene dimers was developed. In a stereoconvergent procedure, various bromocyclobutenes were readily dimerized in good yields, with good diastereoselectivities and broad functional group tolerance. Notably, the presence of a carbonyl group in the starting material appears to dictate diastereoselectivity.
引用
收藏
页码：355 / 359
页数：5
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