Effect of COVID-19 Pandemic on Female Sexual Function: A Systematic Review and Meta-analysis

Context: Since sexual function is significantly influenced by tension, fear, and melancholy, all of which are intensified throughout epidemics, coronavirus disease 2019 (COVID-19) globally can also affect individuals' sexual function and life. The strong relationship between sexual dysfunction and quality of life disorders has made it an important public health concern. Objectives: The current study was conducted to assess female sexual function throughout the COVID-19 quarantine. Evidence Acquisition: ScienceDirect, Web of Science, PubMed, Scopus, and Google Scholar databases were searched with no language limitations. Two independent researchers reviewed all relevant articles published until November 30, 2021. Finally, 22 articles were included in the study, 13 of which were eligible for meta-analysis. The data were combined using meta-analysis and a random effect model. A Begg's funnel plot and Egger's test were used to check the potential bias of publication. Results: The mean score of the female sexual function index (FSFI) was 23.34 (95% confidence interval: 21.17 - 25.52) using the random effect model. Out of the 6 studies that reported the FSFI scores before and throughout the COVID-19 crisis, 5 studies indicated a statistically significant drop in the mean scores of female sexual function throughout COVID-19, contrasting with before the epidemic. Most studies comparing the repetition of sexual activity before and through the COVID-19 epidemic reported a decrease in the repetition of sexual activity throughout the epidemic. Conclusions: Adverse psychological outcomes and restrictions caused by the COVID-19 crisis decreased female sexual function and the repetition of sexual activity. Health policymakers worldwide should scheme and execute helpful syllabi and interventions to reduce the adverse impact of the COVID-19 epidemic on the sexual health of individuals.