Cardinal v.3: a versatile open-source software for mass spectrometry imaging analysis

被引：10

作者：

Bemis, Kylie Ariel ^{[1
]}

Foll, Melanie Christine ^{[1
,2
,3
,4
]}

Guo, Dan ^{[1
]}

Lakkimsetty, Sai Srikanth ^{[1
]}

Vitek, Olga ^{[1
]}

机构：

[1] Northeastern Univ, Khoury Coll Comp Sci, Boston, MA 02115 USA

[2] Univ Freiburg, Fac Med, Med Ctr, Inst Surg Pathol, Freiburg, Germany

[3] German Canc Consortium DKTK, Heidelberg, Germany

[4] German Canc Res Ctr, Heidelberg, Germany

来源：

NATURE METHODS | 2023年 / 20卷 / 12期

关键词：

SEGMENTATION; IONS;

D O I：

10.1038/s41592-023-02070-z

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Cardinal v.3 is an open-source software for reproducible analysis of mass spectrometry imaging experiments. A major update from its previous versions, Cardinal v.3 supports most mass spectrometry imaging workflows. Its analytical capabilities include advanced data processing such as mass recalibration, advanced statistical analyses such as single-ion segmentation and rough annotation-based classification, and memory-efficient analyses of large-scale multitissue experiments.

引用

页码：1883 / 1886

页数：12

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