Engineered lanthanide-based nanomaterials as a novel bio-probe for in vivo dual-modal imaging

被引：2

作者：

Xiang, Lijun ^{[1
]}

Sun, Yuqing ^{[1
]}

Wang, Yong ^{[2
]}

Wu, Jianan ^{[1
]}

Li, Kexin ^{[1
]}

Zhou, Longjiao ^{[1
]}

Zhang, Mingzhu ^{[1
]}

机构：

[1] Anqing Normal Univ, Sch Life Sci, Prov Key Lab Biodivers Study & Ecol Conservat Sout, Anqing 246011, Peoples R China

[2] Wannan Med Coll, Affliated Hosp 1, Yijishan Hosp, Dept Intervent Therapy, Wuhu, Peoples R China

来源：

JOURNAL OF LUMINESCENCE | 2023年 / 261卷

关键词：

Lanthanide-based nanomaterials; Upconversion luminescence; X-ray absorption ability; Dual-modal imaging; NANOPARTICLES;

D O I：

10.1016/j.jlumin.2023.119908

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Developing the multifunctional bio-probe for clinical diagnosis and research remains urgently demanded and greatly challenging. Herein, we report a new dual-modal bio-probe PEG-modified Sr2YbF7: 0.2%Er3+/0.8%Tm3+ (abbreviated as SYF@PEG), which is prepared by a simply one-pot solvothermal method. SYF@PEG with small size can integrate intense red-light emission, superior X-ray absorption ability, high photostability, excellent cell membrane permeability and low toxicity via adopting the apropos lanthanides/modifier and optimizing the content. Importantly, SYF@PEG successfully realizes in vitro/vivo dual-modal imaging of upconversion luminescence (UCL) and X-ray computed tomography (CT), which would be a potential bio-probe for clinical diagnosis.

引用

页数：7

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