Epithelial-mesenchymal transition

被引：0
|
作者：
Kubik, Joanna [1 ]
Pawlak, Kamil [1 ]
机构：
[1] Med Univ Lublin, Independent Med Biol Unit, Lublin, Poland
来源：
CURRENT ISSUES IN PHARMACY AND MEDICAL SCIENCES | 2023年 / 36卷 / 01期
关键词：
epithelial-mesenchymal transition; cancer metastasis; circulating tumor cells; epithelial markers;
D O I：
10.2478/cipms-2023-0005
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The process of epithelial-mesenchymal transition (EMT) occurs in both physiological and pathological states, and there are increasing links between EMT and tumor progression. During this process, dynamic changes in cell organization and function occur that promote migration and invasion. A better understanding of the mechanism of plastic EMT may help develop novel targeted therapies that can help treat cancers of varying degrees of malignancy. Our review helps to systematize knowledge of the molecular and biochemical mechanisms involved in the EMT process in both tumor and physiological backgrounds.
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页码：18 / 20
页数：3
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