Effect of TP53 co-mutation in non-small cell lung cancer (NSCLC) with driver mutations

被引：1
|
作者：
Feng, J. [1 ]
Hueniken, K. [2 ]
Fan, Z. [1 ]
Faour, E. [1 ]
Corke, L. [1 ]
Leighl, N. [1 ]
Liu, G. [1 ]
Bradbury, P. [1 ]
Sacher, A.
Eng, L.
Stockley, T. [3 ]
Tsao, M-S. [1 ]
Shepherd, F. A. [1 ]
机构：
[1] UHN Univ Hlth Network, Med Oncol, Princess Margaret Canc Ctr, Toronto, ON, Canada
[2] UHN Univ Hlth Network, Biostast, Princess Margaret Canc Ctr, Toronto, ON, Canada
[3] UHN Univ Hlth Network, Lab Med Program, Toronto, ON, Canada
来源：
ANNALS OF ONCOLOGY | 2023年 / 34卷
关键词：
D O I：
10.1016/j.annonc.2023.09.2386
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1353P
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Prognostic effects of TP53 variants co-occuring in patients with HER2-mutated non-small cell lung cancer (NSCLC)
    Feng, Jamie
    Hueniken, Katrina
    Fan, Zhen
    Corke, Lucy
    Leighl, Natasha B.
    Liu, Geoffrey
    Bradbury, Penelope Ann
    Sacher, Adrian G.
    Eng, Lawson
    Stockley, Tracy
    Tsao, Ming Sound
    Shepherd, Frances A.
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [42] Nondisruptive mutations of TP53 and overall survival (OS) in advanced non-small-cell lung cancer (NSCLC) patients (p)
    Costa, Enric Carcereny
    Bertran-Alamillo, Jordi
    Molina-Vila, Miguel Angel
    Gervais, Radj
    Massuti, Bartomeu
    Bonanno, Laura
    Moran, Teresa
    Majem, Margarita
    Felip, Enriqueta
    Garcia-Campelo, M. Rosario
    Vergnenegre, Alain
    Ramirez, Santiago Viteri
    Gasco, Amaya
    Wannesson, Luciano
    Mayo-de las Casas, Clara
    Pujantell-Pastor, Laia
    Favaretto, Adolfo G.
    Karachaliou, Niki
    Rosell, Rafael
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [43] Impact on KRAS-subtypes and TP53 mutations on the prognostic value of KRAS/KEAP1 comutations in non-small cell lung cancer (NSCLC)
    Scheffler, M.
    Frank, R.
    Ihle, M. A.
    Abdulla, D. S.
    Koleczko, S.
    Nogova, L.
    Holzem, A.
    Chanra, T.
    Riedel, R.
    Michels, S.
    Fischer, R. N.
    Kron, A.
    Merkelbach-Bruse, S.
    Buettner, R.
    Wolf, J.
    ANNALS OF ONCOLOGY, 2019, 30 : 55 - 55
  • [44] The Correlation Between K-Ras Mutant Subsets with TP53 Mutation and PD-L1 in Non-Small Cell Lung Cancer (NSCLC)
    Karim, N. Abdel
    Onuoha, C.
    Eldesouki, I.
    Ahmad, I.
    Mamdani, H.
    Spira, A.
    Naqash, A. R.
    JOURNAL OF THORACIC ONCOLOGY, 2019, 14 (10) : S650 - S650
  • [45] Multiregion sequencing reveals the intratumor heterogeneity of driver mutations in TP53-driven non-small cell lung cancer
    Zhang, Le-Le
    Kan, Mengyuan
    Zhang, Man-Man
    Yu, Sha-Sha
    Xie, Hui-Jun
    Gu, Zhao-Hui
    Wang, Hai-Ning
    Zhao, Shuang-Xia
    Zhou, Guang-Biao
    Song, Huai-Dong
    Zheng, Cui-Xia
    INTERNATIONAL JOURNAL OF CANCER, 2017, 140 (01) : 103 - 108
  • [46] EGFR exon 20 insertions in non-small cell lung cancer (NSCLC): Impact of TP53 mutation status and value of immune checkpoint blockade (ICB)
    Kron, A.
    Scheffler, M.
    Ihle, M.
    Michels, S.
    Sueptitz, J.
    Prang, D.
    Jakobs, F.
    Nogova, L.
    Fischer, R. N.
    Eisert, A. K.
    Riedel, R.
    Kron, F.
    Hillmer, A.
    Loges, S.
    Merkelbach-Bruse, S.
    Buettner, R.
    Wolf, J.
    ANNALS OF ONCOLOGY, 2022, 33 (07) : S1006 - S1006
  • [47] Effect of Coexisting KRAS and TP53 Mutations in Patients Treated With Chemotherapy for Non-small-cell Lung Cancer
    Tomasini, Pascale
    Mascaux, Celine
    Jao, Kevin
    Labbe, Catherine
    Kamel-Reid, Suzanne
    Stockley, Tracy
    Hwang, David M.
    Leighl, Natasha B.
    Liu, Geoffrey
    Bradbury, Penelope A.
    Pintilie, Melania
    Tsao, Ming-Sound
    Shepherd, Frances A.
    CLINICAL LUNG CANCER, 2019, 20 (03) : E338 - E345
  • [48] Prognostic Impact of TP53 Mutations in Metastatic Nonsquamous Non-small-cell Lung Cancer
    Mathiot, Laurent
    Nigen, Benoit
    Goronflot, Thomas
    Hiret, Sandrine
    Doucet, Ludovic
    Pons-Tostivint, Elvire
    Bennouna, Jaafar
    Denis, Marc G.
    Herbreteau, Guillaume
    Raimbourg, Judith
    CLINICAL LUNG CANCER, 2024, 25 (03) : 244 - 253.e2
  • [49] Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer TP53 mutations
    Fukuda, Koji
    Takeuchi, Shinji
    Arai, Sachiko
    Nanjo, Shigeki
    Sato, Shigeki
    Kotani, Hiroshi
    Kita, Kenji
    Nishiyama, Akihiro
    Sakaguchi, Hiroyuki
    Ohtsubo, Koshiro
    Yano, Seiji
    CELL REPORTS MEDICINE, 2024, 5 (06)
  • [50] Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer
    Montserrat Sanchez-Cespedes
    Andre L Reed
    Martin Buta
    Li Wu
    William H Westra
    James G Herman
    Stephen C Yang
    Jin Jen
    David Sidransky
    Oncogene, 1999, 18 : 5843 - 5849
12345