Effects of intradialytic exercise in combination with melatonin supplementation on functional capacity, postural balance, and quality of life in hemodialysis patients

被引:2
|
作者
Marzougui, Houssem [1 ,2 ]
Maaloul, Rami [1 ,2 ]
Ben Dhia, Imen [2 ,3 ]
Toumi, Salma [4 ]
Kammoun, Khawla [4 ,5 ]
Ben Hmida, Mohamed [4 ,5 ]
Ayadi, Fatma [1 ]
Turki, Mouna [1 ,6 ]
Elleuch, Mohamed Habib [3 ]
Ghroubi, Sameh [3 ]
Hammouda, Omar [1 ,7 ]
机构
[1] Univ Sfax, Fac Med, Res Lab Mol Bases Human Pathol LR19ES13, Sfax, Tunisia
[2] Univ Sfax, High Inst Sport & Phys Educ Sfax, Sfax, Tunisia
[3] Univ Sfax, Fac Med, Res Lab Evaluat & Management Musculoskeletal Syst, Sfax, Tunisia
[4] Univ Sfax, Nephrol Dept, CHU Hedi Chaker, Sfax, Tunisia
[5] Univ Sfax, Fac Med, Res Lab Renal Pathol LR19ES11, Sfax, Tunisia
[6] Univ Sfax, Biochem Lab, CHU Habib Bourguiba, Sfax, Tunisia
[7] Paris Nanterre Univ, Interdisciplinary Lab Neurosci Physiol & Psychol P, UFR STAPS, UPL, Nanterre, France
关键词
exogenous melatonin; intradialytic exercise; muscle strength; postural sway; renal failure; MUSCLE ATROPHY; 6-MINUTE WALK; CROSS-OVER; SLEEP; RESISTANCE; DIALYSIS; HEALTH; ASSOCIATION; STRENGTH; PROGRAM;
D O I
10.1111/1744-9987.13964
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction: We evaluated the effect of intradialytic concurrent (resistance-endurance) training combined with melatonin (MEL) supplementation on functional capacity, muscle strength, postural balance, and quality of life (QoL) in hemodialysis (HD) patients.Methods: Thirty-three HD patients were randomized into three groups: Exercise (EX)-MEL (n = 11); EX-Placebo (PLA) (n = 11) and Control (C)-PLA (n = 11). Participants included in the EX-MEL and EX-PLA groups were submitted to concurrent training for 12 weeks.Results: EX-MEL and EX-PLA improved functional capacity, muscle strength, QoL, and postural balance parameters in eyes open and eyes closed conditions. Parameters of postural balance in the dual task condition were improved only in EX-MEL. EX-MEL induced better results in some domains of QoL compared with EX-PLA.Conclusion: Intradialytic concurrent training induced beneficial effects on physical function, muscle strength, postural balance, and QoL in HD patients. MEL supplementation combined with intradialytic exercise lead to better improvements in postural balance and QoL.
引用
收藏
页码:669 / 681
页数:13
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