Prevalence of latent Mycobacterium tuberculosis infection in hematopoietic stem cell transplantation comparing tuberculin skin test and interferon-gamma release assay

被引：0
|
作者：
Castro-Lima, Victor A. C. [1 ]
Santos, Ana Paula T. [2 ]
Musqueira, Priscila T. [3 ]
Maluf, Natalya Z. [2 ]
Ramos, Jessica F. [3 ]
Mariano, Livia [3 ]
Rocha, Vanderson [3 ]
Costa, Silvia F. [1 ]
机构：
[1] Univ Sao Paulo, Dept Molestias Infecciosas & Parasitarias, Fac Med, Ave Dr Eneas Carvalho Aguiar, 470, Sao Paulo, SP, Brazil
[2] Univ Sao Paulo, Div Lab Cent, Hosp Clin, Fac Med, Sao Paulo, Brazil
[3] Univ Sao Paulo, Serv Hematol Hemoterapia & Terapia Celular, Hosp Clin, Fac Med, Sao Paulo, Brazil
来源：
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2023年 / 42卷 / 07期
关键词：
Hematopoietic stem cell transplantation; Immunocompromised host; Interferon-gamma release tests; Tuberculosis; Tuberculin; RECIPIENTS;
D O I：
10.1007/s10096-023-04613-w
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The aim of this study was to evaluate the prevalence of latent Mycobacterium tuberculosis infection in hematopoietic stem cell transplantation candidates, using tuberculin skin test and QuantiFERON-TB Gold-Plus, in a high-burden tuberculosis country. Adult candidates for hematopoietic stem cell transplantation performed both tests before and those submitted to transplantation were followed up for 12 months. The prevalence of latent Mycobacterium tuberculosis infection was 17.1% and a moderate agreement between QuantiFERON-TB Gold-Plus and tuberculin skin test was observed in this population. Previous tuberculosis exposure was a risk factor for latent Mycobacterium tuberculosis infection. No cases of tuberculosis were diagnosed during follow-up period.
引用
收藏
页码：899 / 902
页数：4
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