Monoclonal gammopathies of renal significance

被引：3
|
作者：
Gnanasampanthan, Sahana [1 ]
Kousios, Andreas [1 ,2 ,3 ]
机构：
[1] Hammersmith Hosp, Imperial Coll Healthcare NHS Trust, London, England
[2] Imperial Coll, London, England
[3] Hammersmith Hosp, Imperial Coll Healthcare NHS Trust, West London Renal & Transplant Ctr, Du Cane Rd, London W10 0HS, England
来源：
CLINICAL MEDICINE | 2023年 / 23卷 / 03期
关键词：
Paraprotein-related renal disease; monoclonal immunoglobulins; monoclonal gammopathies of renal significance; Bence-jones protein; chronic kidney disease; PROLIFERATIVE GLOMERULONEPHRITIS;
D O I：
10.7861/clinmed.2023-RM3
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The term monoclonal gammopathies of renal significance (MGRS) encompasses a group of renal histopathological lesions fulfilling two criteria: (a) they are caused by nephrotoxic monoclonal immunoglobulins and (b) the monoclonal immunoglobulins are produced by small B-cell or plasma cell clones which do not meet the criteria for multiple myeloma or malignant lymphoma. Here, we provide a review of the MGRS definition and related terminology and elaborate on the diagnostic approach and treatment principles from the general physician perspective.
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页码：250 / 253
页数：4
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