A genetic basis for asymptomatic SARS-CoV-2 infection

被引:0
|
作者
Augusto, Danillo G. [1 ]
Hollenbach, Jill A. [2 ]
机构
[1] Univ North Carolina Charlotte, Charlotte, NC 28223 USA
[2] Univ Calif San Francisco, San Francisco, CA USA
关键词
SARS-CoV-2; Genetics; Infection; Immunology;
D O I
10.1038/d41586-023-02102-w
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A common genetic variant of the human leukocyte antigen (HLA) complex, a family of genes involved in the immune response, is associated with an absence of symptoms during SARS-CoV-2 infection. Previous exposure to cold viruses seems to confer this immunity.
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Viral transmission in asymptomatic cases of SARS-CoV-2 infection
    Grall, Isabelle
    Alloui, Chakib-Ahmed
    Tandjaoui-Lambiotte, Yacine
    Deslandes, Antoine
    Seytre, Delphine
    Chappe, Julie
    Carbonnelle, Etienne
    Brichler, Segolene
    Jacolot, Anne
    Zahar, Jean-Ralph
    Lomont, Alexandra
    JOURNAL OF INFECTION, 2021, 82 (02) : 308 - 310
  • [22] A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection
    Evangelos Andreakos
    Laurent Abel
    Donald C. Vinh
    Elżbieta Kaja
    Beth A. Drolet
    Qian Zhang
    Cliona O’Farrelly
    Giuseppe Novelli
    Carlos Rodríguez-Gallego
    Filomeen Haerynck
    Carolina Prando
    Aurora Pujol
    Helen C. Su
    Jean-Laurent Casanova
    András N. Spaan
    Nature Immunology, 2022, 23 : 159 - 164
  • [23] A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection
    Andreakos, Evangelos
    Abel, Laurent
    Vinh, Donald C.
    Kaja, Elzbieta
    Drolet, Beth A.
    Zhang, Qian
    O'Farrelly, Cliona
    Novelli, Giuseppe
    Rodriguez-Gallego, Carlos
    Haerynck, Filomeen
    Prando, Carolina
    Pujol, Aurora
    Su, Helen C.
    Casanova, Jean-Laurent
    Spaan, Andras N.
    Bastard, Paul
    Biggs, Catherine M.
    Bigio, Benedetta
    Boisson, Bertrand
    Bolze, Alexandre
    Bondarenko, Anastasiia
    Brodin, Petter
    Chakravorty, Samya
    Christodoulou, John
    Cobat, Aurelie
    Condino-Neto, Antonio
    Constantinescu, Stefan N.
    Feldman, Hagit Baris
    Fellay, Jacques
    Halwani, Rabih
    Jouanguy, Emmanuelle
    Lau, Yu-Lung
    Meyts, Isabelle
    Mogensen, Trine H.
    Okada, Satoshi
    Okamoto, Keisuke
    Ozcelik, Tayfun
    Pan-Hammarstrom, Qiang
    Planas, Anna M.
    Puel, Anne
    Quintana-Murci, Lluis
    Renia, Laurent
    Resnick, Igor
    Sediva, Anna
    Shcherbina, Anna
    Slaby, Ondrej
    Tancevski, Ivan
    Turvey, Stuart E.
    Uddin, K. M. Furkan
    van de Beek, Diederik
    NATURE IMMUNOLOGY, 2022, 23 (02) : 159 - 164
  • [24] Genetic Control of Human Infection with SARS-CoV-2
    A. N. Kucher
    N. P. Babushkina
    A. A. Sleptcov
    M. S. Nazarenko
    Russian Journal of Genetics, 2021, 57 : 627 - 641
  • [25] Genetic Control of Human Infection with SARS-CoV-2
    Kucher, A. N.
    Babushkina, N. P.
    Sleptcov, A. A.
    Nazarenko, M. S.
    RUSSIAN JOURNAL OF GENETICS, 2021, 57 (06) : 627 - 641
  • [26] Intranasal Infection of Ferrets with SARS-CoV-2 as a Model for Asymptomatic Human Infection
    Everett, Helen E.
    Lean, Fabian Z. X.
    Byrne, Alexander M. P.
    van Diemen, Pauline M.
    Rhodes, Shelley
    James, Joe
    Mollett, Benjamin
    Coward, Vivien J.
    Skinner, Paul
    Warren, Caroline J.
    Bewley, Kevin R.
    Watson, Samantha
    Hurley, Shellene
    Ryan, Kathryn A.
    Hall, Yper
    Simmons, Hugh
    Nunez, Alejandro
    Carroll, Miles W.
    Brown, Ian H.
    Brookes, Sharon M.
    VIRUSES-BASEL, 2021, 13 (01):
  • [27] A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection
    Israeli, Eitan
    ISRAEL MEDICAL ASSOCIATION JOURNAL, 2023, 25 (09): : 589 - 589
  • [28] The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions?
    Boyton, Rosemary J.
    Altmann, Daniel M.
    NATURE REVIEWS IMMUNOLOGY, 2021, 21 (12) : 762 - 768
  • [29] Severe acquired haemophilia associated with asymptomatic SARS-CoV-2 infection
    Wang, Kevin Y.
    Shah, Pratik
    Roarke, Dennis T.
    Shakil, Shams A.
    BMJ CASE REPORTS, 2021, 14 (07)
  • [30] Waning Antibody Responses in Asymptomatic and Symptomatic SARS-CoV-2 Infection
    Choe, Pyoeng Gyun
    Kang, Chang Kyung
    Suh, Hyeon Jeong
    Jung, Jongtak
    Song, Kyoung-Ho
    Bang, Ji Hwan
    Kim, Eu Suk
    Kim, Hong Bin
    Park, Sang Won
    Kim, Nam Joong
    Park, Wan Beom
    Oh, Myoung-Don
    EMERGING INFECTIOUS DISEASES, 2021, 27 (01) : 327 - 329