Male factor infertility and assisted reproductive technologies: indications, minimum access criteria and outcomes

被引：21
|
作者：
Mazzilli, R. [1 ,2 ]
Rucci, C. [2 ,3 ]
Vaiarelli, A. [2 ]
Cimadomo, D. [2 ]
Ubaldi, F. M. [2 ]
Foresta, C. [4 ]
Ferlin, A. [4 ]
机构：
[1] Sapienza Univ Rome, St Andrea Hosp, Dept Clin & Mol Med, Androl Unit, Via Grottarossa, 1036-1039, I-00100 Rome, Italy
[2] GeneraLife IVF, Clin Valle Giulia, Rome, Italy
[3] Univ Rome TorVergata, Dept Surg Sci, Gynecol Unit, Rome, Italy
[4] Univ Padua, Dept Med, Unit Androl & Reprod Med, Padua, Italy
来源：
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION | 2023年 / 46卷 / 06期
关键词：
Assisted reproductive technology (ART); Severe male factor; Azoospermia; Oligozoospermia; ICSI-IVF; INTRAUTERINE INSEMINATION; LIVE BIRTH; SPERM; ANEUPLOIDY; MEN; PREVALENCE; MANAGEMENT; MUTATIONS; ANDROLOGY; SUCCESS;
D O I：
10.1007/s40618-022-02000-4
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
BackgroundInfertility, which is defined as the inability to conceive after at least 12 months of regular unprotected sexual intercourses, affects about 15-20% of couples worldwide and a male factor is involved in about half of the cases. The development of assisted reproductive technology (ART) made it possible to conceive also to individuals affected from severe oligospermia or azoospermia. However, the impact of the male factor on embryo development, implantation, prevalence of chromosomal abnormalities, genetic and epigenetic alterations, and clinical and obstetric outcomes is still controversial.PurposeThis narrative review examines the indications, minimum access criteria, and outcomes by individual ART technique in relation to the male factor.
引用
收藏
页码：1079 / 1085
页数：7
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