Genome-wide CRISPR/Cas9 screen identifies regulators of BCMA expression on multiple myeloma cells

被引:2
|
作者
Ajore, Ram [1 ,2 ]
Mattsson, Jenny [1 ,2 ,3 ]
Pertesi, Maroulio [1 ,2 ]
Ekdahl, Ludvig [1 ,2 ]
Ali, Zain [1 ,2 ]
Hansson, Markus [1 ,4 ]
Nilsson, Bjoern [1 ,2 ,5 ]
机构
[1] Lund Univ, Dept Lab Med, Div Hematol & Transfus Med, S-22184 Lund, Sweden
[2] Lund Univ, Lund Stem Cell Ctr, S-22184 Lund, Sweden
[3] BioInvent Int AB, Ideongatan 1, S-22370 Lund, Sweden
[4] Gothenburg Univ, Sahlgrenska Acad, Dept Internal Med & Clin Nutr, S-41346 Gothenburg, Sweden
[5] Broad Inst, Cambridge, MA 02142 USA
基金
芬兰科学院; 瑞典研究理事会;
关键词
GAMMA-SECRETASE; MATURATION ANTIGEN; APH-1; TRANSCRIPTION; PRESENILIN; NICASTRIN; RECEPTOR; HEXIM1; THERAPY; PATHWAY;
D O I
10.1038/s41408-024-00986-z
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页数:4
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