Fully automated comprehensive genomic profiling for detection of cancer variants, gene fusions, and complex oncology endpoints

被引：0
|
作者：
Lowman, Geoffrey Marc
Cyanam, Dinesh
Norris, Emily
Toro, Michelle
Nemes, Coleen
Puranik, Tanaya
Zhu, Yan
Phan, Alex
Wong, Derek
Bernado, Portia
Kralcheva, Anelia
Nallandhighal, Srinivas
Pickle, Loni
Bigley, April
Gupta, Mohit
Jin, Ying
El-Difrawy, Sameh
Marcovitz, Amir
Zare, Fatima
Scafe, Charles
Tseng, Yu-Ting
Guo, Jianjun
Mittal, Vinay
Myrand, Scott
Williams, Paul
Ingerman, Eugene
Wong-Ho, Elaine
Sadis, Seth
Andersen, Mark
Bennett, Rob
机构：
来源：
CANCER RESEARCH | 2023年 / 83卷 / 07期
关键词：
D O I：
10.1158/1538-7445.AM2023-232
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
232
引用
收藏
页数：3
相关论文
共 50 条
  • [41] The Impact of Prior Single-Gene Testing on Comprehensive Genomic Profiling Results for Patients with Non-Small Cell Lung Cancer
    Nesline, Mary K.
    Subbiah, Vivek
    Previs, Rebecca A.
    Strickland, Kyle C.
    Ko, Heidi
    Depietro, Paul
    Biorn, Michael D.
    Cooper, Maureen
    Wu, Nini
    Conroy, Jeffrey
    Pabla, Sarabjot
    Zhang, Shengle
    Wallen, Zachary D.
    Sathyan, Pratheesh
    Saini, Kamal
    Eisenberg, Marcia
    Caveney, Brian
    Severson, Eric A.
    Ramkissoon, Shakti
    ONCOLOGY AND THERAPY, 2024, 12 (02) : 329 - 343
  • [42] A Paradigm Shift in Non-Small-Cell Lung Cancer (NSCLC) Diagnostics: From Single Gene Tests to Comprehensive Genomic Profiling
    Zameer, Ushna
    Shaikh, Wajiha
    Khan, Abdul Moiz
    CANCER INFORMATICS, 2024, 23
  • [43] Analytical validation of solid tumor fusion gene detection in a comprehensive NGS-based clinical cancer genomic test
    Yelensky, Roman
    Donahue, Amy
    Otto, Geoff
    Nahas, Michelle
    He, Jie
    Juhn, Frank
    Downing, Sean
    Frampton, Garrett M.
    Chmielecki, Juliann
    Ross, Jeffrey S.
    Zakowski, Maureen
    Ladanyi, Marc
    Miller, Vincent A.
    Stephens, Philip J.
    Lipson, Doron
    CANCER RESEARCH, 2014, 74 (19)
  • [44] Analysis of Simple and Complex Variants and Biomarkers for Comprehensive Genomic Profiling (CGP) of Solid Tumors and Hematologic Malignancies Using a Single NGS Workflow from FFPE and cfDNA Samples
    Samara, R.
    Jiang, Q.
    Wilt, G.
    Gregersen, V.
    Schauser, L.
    Shaffer, J.
    Lader, E.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2020, 22 (11): : S93 - S93
  • [45] Identification of potential germline variants (GV) on tumor comprehensive genomic profiling (CGP) in patients with advanced breast cancer (BC): BRCA1/2 and beyond
    Tierno, Marni B.
    Dougherty, Kali C.
    Gornstein, Erica
    Pavlick, Dean C.
    Schrock, Alexa
    Oxnard, Geoff R.
    CANCER RESEARCH, 2022, 82 (04)
  • [46] Performance Characteristics of a Targeted Sequencing Platform for Simultaneous Detection of Single Nucleotide Variants, Insertions/Deletions, Copy Number Alterations, and Gene Fusions in Cancer Genome
    Park, Kyung
    Tran, Hung
    Eng, Kenneth W.
    Ramazanoglu, Sinan
    Rolon, Rebecca M. Marrero
    Scognamiglio, Theresa
    Borczuk, Alain
    Mosquera, Juan Miguel
    Pan, Qiulu
    Sboner, Andrea
    Rubin, Mark A.
    Elemento, Olivier
    Rennert, Hanna
    Fernandes, Helen
    Song, Wei
    ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 2020, 144 (12) : 1535 - 1546
  • [47] Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing
    Cheng, Donavan T.
    Prasad, Meera
    Chekaluk, Yvonne
    Benayed, Ryma
    Sadowska, Justyna
    Zehir, Ahmet
    Syed, Aijazuddin
    Wang, Yan Elsa
    Somar, Joshua
    Li, Yirong
    Yelskaya, Zarina
    Wong, Donna
    Robson, Mark E.
    Offit, Kenneth
    Berger, Michael F.
    Nafa, Khedoudja
    Ladanyi, Marc
    Zhang, Liying
    BMC MEDICAL GENOMICS, 2017, 10
  • [48] Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing
    Donavan T. Cheng
    Meera Prasad
    Yvonne Chekaluk
    Ryma Benayed
    Justyna Sadowska
    Ahmet Zehir
    Aijazuddin Syed
    Yan Elsa Wang
    Joshua Somar
    Yirong Li
    Zarina Yelskaya
    Donna Wong
    Mark E. Robson
    Kenneth Offit
    Michael F. Berger
    Khedoudja Nafa
    Marc Ladanyi
    Liying Zhang
    BMC Medical Genomics, 10
  • [49] Comprehensive NGS profiling to enable detection of ALK gene rearrangements and MET amplifications in non-small cell lung cancer
    Clave, Sergi
    Jackson, Jennifer B.
    Salido, Marta
    Kames, Jacob
    Gerding, Kelly M. R.
    Verner, Ellen L.
    Kong, Eric F.
    Weingartner, Elizabeth
    Gibert, Joan
    Hardy-Werbin, Max
    Rocha, Pedro
    Riera, Xenia
    Torres, Erica
    Hernandez, James
    Cerqueira, Gustavo
    Nichol, Donna
    Simmons, John
    Taus, Alvaro
    Pijuan, Lara
    Bellosillo, Beatriz
    Arriola, Edurne
    FRONTIERS IN ONCOLOGY, 2023, 13
  • [50] Comprehensive targeted gene profiling to determine the genomic signature likely to drive progression of high-grade nonmuscle invasive bladder cancer to muscle invasive bladder cancer
    Alkhateeb, Abedalrhman
    Atikukke, Govindaraja
    Porter, Lisa
    Fifield, Bre-Anne
    Cavallo-Medved, Dora
    Facca, Julianna
    El-Gohary, Yasser
    Zhang, Tianmin
    Hamzeh, Osamah
    Rueda, Luis
    Kanjeekal, Sindu Mary
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (06)
12345