Pulmonary Nodular Lymphoid Hyperplasia Evaluated with Bronchoalveolar Lavage Fluid Findings: A Case Report and Review of the Literature on Japanese Patients

被引：2

作者：

Moriyama, Sakiko ^{[1
]}

Kido, Takashi ^{[1
]}

Sakamoto, Noriho ^{[1
]}

Fuchigami, Mai ^{[2
]}

Tokito, Takatomo ^{[1
]}

Okuno, Daisuke ^{[1
]}

Miyamura, Takuto ^{[1
]}

Nakashima, Shota ^{[1
]}

Hara, Atsuko ^{[1
]}

Ishimoto, Hiroshi ^{[1
]}

Imaizumi, Yoshitaka ^{[3
]}

Tsuruda, Kazuto ^{[2
]}

Yanagihara, Katsunori ^{[2
]}

Fukuoka, Junya ^{[4
]}

Mukae, Hiroshi ^{[1
]}

机构：

[1] Nagasaki Univ, Grad Sch Biomed Sci, Dept Resp Med, Nagasaki, Japan

[2] Nagasaki Univ Hosp, Dept Lab Med, Nagasaki, Japan

[3] Nagasaki Univ Hosp, Dept Hematol, Nagasaki, Japan

[4] Nagasaki Univ, Grad Sch Biomed Sci, Dept Pathol, Nagasaki, Japan

来源：

INTERNAL MEDICINE | 2023年 / 62卷 / 01期

关键词：

bronchoalveolar lavage fluid; gene translocation; immunoglobulin heavy chain; mucosa-associated lymphoid tissue lymphoma; pulmonary nodular lymphoid hyperplasia; MALT LYMPHOMA; DISEASE; LYMPHOCYTES; LUNG; CLONALITY;

D O I：

10.2169/internalmedicine.9310-21

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Pulmonary nodular lymphoid hyperplasia (PNLH) is a very rare disease, and it is difficult to diagnose PNLH and distinguish it from mucosa-associated lymphoid tissue (MALT) lymphoma. In addition, information on bronchoalveolar lavage fluid (BALF) analyses is lacking. We herein report a 36-year-old Japanese woman diagnosed with PLNH by a surgical biopsy and analysis of BALF. The BALF showed an increase in B-cell marker-positive lymphocytes, normal patterns of B-cell clonality, mucosa-associated lymphoid tissue 1 gene, and immunoglobulin heavy chain at 14q32 translocations. We also reviewed Japanese cases of PNLH described in Japanese or English to explore the characteristics of such cases.

引用

页码：95 / 102

页数：8

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