Smartphone-integrated ratiometric sensing strategy for on-line quantitation of tetracycline based on functionalized g-C3N4/Eu electrospun film

On-line quantitation of tetracycline (TC) is significant to ensure environmental health and food security. Hence, a novel smartphone-integrated ratiometric sensing platform for on-line quantitative analysis of TC was designed. A CitNa-functionalized g-C3N4/Eu3+ (g-C3N4/CitNa/Eu) composites with blue and red dual-emissive feature were fabricated as dual indicators for shielding background interference, enhancing anti-interference capability. The fluorescent response (F620/F450) ratio and TC concentration demonstrated good linear relationship ranged from 0.0 to 100.0 mu M with a detection limit of 1.96 nM. Furthermore, the combination of g-C3N4/CitNa/Eu and polyacrylonitrile polymers forming electrospun film was achieved via electrospinning method. Smartphoneintegrated ratiometric sensing platform was developed based on the fluorescent color of electrospun film from blue to light red with TC. This solid sensing platform achieved excellent sensitivity with a detection limit of 7.42 nM. Combining the solid ratiometric fluorescent film with smartphone reader provides a potential way for online quantitation of TC in food and other fields.