Gut Microbiota Conditioning Promotes Anti-Tumor Immunity and Responsiveness to Immunological Checkpoint Blockade in Colorectal Cancer

被引：0
|
作者：
Basso, C. [1 ]
Cianfarani, A. [2 ]
Djordjevic, J. [1 ]
Sorrenti, E. [1 ]
Galafassi, J. [3 ]
Roesel, R. [3 ]
Christoforidis, D. [3 ]
Majno-Hurst, P. E. [3 ]
Iezzi, G. [2 ]
机构：
[1] Univ Svizzera Italiana, Bellinzona, Switzerland
[2] Ente Osped Cantonale, Bellinzona, Switzerland
[3] Cantonal Hosp Lugano, Dept Visceral Surg, Lugano, Switzerland
来源：
BRITISH JOURNAL OF SURGERY | 2023年 / 110卷 / SUPP 5期
关键词：
D O I：
10.1093/bjs/znad178.025
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
znad178.02
引用
收藏
页数：1
相关论文
共 50 条
  • [21] Tumor cell-derived lactic acid inhibit anti-tumor immunity in the immune checkpoint blockade resistant tumor
    Oh, Wonkyung
    Kim, Alyssa Min Jung
    Sun, Ruoxuan
    Lim, Seung-Oe
    CANCER IMMUNOLOGY RESEARCH, 2022, 10 (01)
  • [22] Blockade of the PPARα metabolic checkpoint with TPST-1120 suppresses tumor growth and stimulates anti-tumor immunity
    Whiting, Chan C.
    Stock, Nick
    Messmer, Davorka
    Olafson, Traci
    Metzger, Derek
    Enstrom, Amanda
    McDevitt, Jennifer
    Spaner, David
    Prasit, Peppi
    Panigrahy, Dipak
    Laport, Ginna
    CANCER RESEARCH, 2019, 79 (13)
  • [23] Current and Prospective Methods for Assessing Anti-Tumor Immunity in Colorectal Cancer
    Nussbaum, Yulia I.
    Manjunath, Yariswamy
    Suvilesh, Kanve N.
    Warren, Wesley C.
    Shyu, Chi-Ren
    Kaifi, Jussuf T.
    Ciorba, Matthew A.
    Mitchem, Jonathan B.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (09)
  • [24] CD24 blockade promotes anti-tumor immunity in oral squamous cell carcinoma
    Zou, Ke-Long
    Lan, Zhou
    Cui, Hao
    Zhao, Yu-Yue
    Wang, Wei-Ming
    Yu, Guang-Tao
    ORAL DISEASES, 2024, 30 (02) : 163 - 171
  • [25] Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity
    Qing Zhang
    Jiacheng Bi
    Xiaodong Zheng
    Yongyan Chen
    Hua Wang
    Wenyong Wu
    Zhengguang Wang
    Qiang Wu
    Hui Peng
    Haiming Wei
    Rui Sun
    Zhigang Tian
    Nature Immunology, 2018, 19 : 723 - 732
  • [26] Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity
    Zhang, Qing
    Bi, Jiacheng
    Zheng, Xiaodong
    Chen, Yongyan
    Wang, Hua
    Wu, Wenyong
    Wang, Zhengguang
    Wu, Qiang
    Peng, Hui
    Wei, Haiming
    Sun, Rui
    Tian, Zhigang
    NATURE IMMUNOLOGY, 2018, 19 (07) : 723 - +
  • [27] PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade
    Srour, Nivine
    Villarreal, Oscar D.
    Hardikar, Swanand
    Yu, Zhenbao
    Preston, Samuel
    Miller, Wilson H., Jr.
    Szewczyk, Magdelena M.
    Barsyte-Lovejoy, Dalia
    Xu, Han
    Chen, Taiping
    Del Rincon, Sonia, V
    Richard, Stephane
    CELL REPORTS, 2022, 38 (13):
  • [28] Bempegaldesleukin in combination with local radiation and systemic checkpoint blockade induces a robust systemic anti-tumor immunity
    Pieper, Alexander
    Rakhmilevich, Alexander
    Spiegelman, Dan
    Patel, Ravi
    Baniel, Claire
    Erbe, Amy
    Hank, Jacquelyn
    Charych, Deborah
    Overwijk, Willem
    Morris, Zachary
    Sondel, Paul
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
  • [29] Systemically Administered Sindbis Virus in Combination with Immune Checkpoint Blockade Induces Curative Anti-tumor Immunity
    Scherwitzl, Iris
    Hurtado, Alicia
    Pierce, Carolyn M.
    Vogt, Sandra
    Pampeno, Christine
    Meruelo, Daniel
    MOLECULAR THERAPY-ONCOLYTICS, 2018, 9 : 51 - 63
  • [30] Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade
    Jiang, Yuying
    Yang, Yongbing
    Hu, Yingchao
    Yang, Rui
    Huang, Jiajia
    Liu, Yi
    Wu, Yuqing
    Li, Sheng
    Ma, Chunmei
    Humphries, Fiachra
    Wang, Bingwei
    Wang, Xi
    Hu, Zhibin
    Yang, Shuo
    CELL REPORTS, 2022, 41 (04):
12345