Ultrasensitive Electrochemical Sensor Based on Vertical Graphene for SARS-CoV-2 Protein N Detection

被引:0
|
作者
Chiriac, Eugen [1 ,2 ]
Adiaconita, Bianca [1 ]
Preda, Petruta [1 ]
Burinaru, Tiberiu [1 ,3 ]
Marculescu, Catalin [1 ]
Pachiu, Cristina [1 ]
Craciun, Gabriel [1 ]
Avram, Andrei [1 ]
Avram, Marioara [1 ]
机构
[1] Natl Inst Res & Dev Microtechnol IMT Bucharest, Voluntari, Romania
[2] Univ Politehn Bucuresti, Bucharest, Romania
[3] Univ Agron Sci & Vet Med Bucharest, Bucharest, Romania
关键词
EIS detection; electrochemical biosensor; graphene; SARS-CoV-2; NANOPARTICLES;
D O I
暂无
中图分类号
TP301 [理论、方法];
学科分类号
081202 ;
摘要
Monitoring and controlling infection is required in order to prevent the progression of the coronavirus severe acute respiratory syndrome 2(SARS-CoV-2). To accomplish this goal, the development and implementation of sensitive, quick and accurate diagnostic methods are essential. Electrochemical sensors have exposed large application possibilities in biological detection due to the advantages of high sensitivity, short time-consuming and specificity. Here, we report the improvement of a sensitive electrochemical sensor capable of detecting the presence of the SARS-CoV-2 virus using graphene-modified interdigitated working electrodes functionalized with antibodies targeting the SARS-CoV-2 nucleocapsid protein (N protein).
引用
收藏
页码:227 / 237
页数:11
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