Takotsubo cardiomyopathy (TC) is a transient condition characterized by left ventricular wall motion abnormalities, ventricular systolic dysfunction, and apical ballooning. When initially presented, the pathology is often erroneously attributed to acute coronary syndrome (ACS) or acute-onset heart failure due to similar symptoms and electrocardiogram (ECG) findings. However, upon further review of imaging, coronary arteries are often void of disease. The highest prevalence of Takotsubo cardiomyopathy is noted in elderly, postmenopausal women who recently experienced an emotionally or physically triggering event. Although the true underlying pathophysiology of Takotsubo cardiomyopathy remains poorly elucidated, a few leading concepts suggest that stress-induced sympathetic responses may lead to catecholamine-induced cardiotoxicity. Other ideologies implicate poor coronary perfusion, neurogenic myocardial stunning, and coronary artery vasospasms. As features of TC are transient, it has an excellent prognosis, and patients see improvement in ventricular function and symptoms within weeks after the initiation of therapy. In this paper, we discuss a case of TC noted incidentally on imaging in a middle-aged female presenting with encephalopathy after a motor vehicle accident.
机构:
Wyckoff Hts Med Ctr, Internal Med, New York, NY 11237 USA
Unity Hlth Hosp, Internal Med, Searcy, AR USAWyckoff Hts Med Ctr, Internal Med, New York, NY 11237 USA
Landa, Eric
Vigandt, Erika
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Brooklyn Hosp Ctr, Internal Med, New York, NY USAWyckoff Hts Med Ctr, Internal Med, New York, NY 11237 USA
Vigandt, Erika
Moron, Luis
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Wyckoff Hts Med Ctr, Internal Med, New York, NY 11237 USAWyckoff Hts Med Ctr, Internal Med, New York, NY 11237 USA
Moron, Luis
Ubhi, Manveer
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Wyckoff Hts Med Ctr, Internal Med, New York, NY 11237 USAWyckoff Hts Med Ctr, Internal Med, New York, NY 11237 USA
Ubhi, Manveer
Fermin, Basilides
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Wyckoff Hts Med Ctr, Internal Med, New York, NY 11237 USAWyckoff Hts Med Ctr, Internal Med, New York, NY 11237 USA
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Medstar Georgetown Univ, Washington Hosp Ctr, Washington, DC 20007 USAMedstar Georgetown Univ, Washington Hosp Ctr, Washington, DC 20007 USA
Patel, Nirav S.
Negi, Smita I.
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Medstar Georgetown Univ, Washington Hosp Ctr, Washington, DC 20007 USAMedstar Georgetown Univ, Washington Hosp Ctr, Washington, DC 20007 USA
Negi, Smita I.
Anand, Aashish
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Univ Maryland, Med Ctr, Baltimore, MD 21201 USAMedstar Georgetown Univ, Washington Hosp Ctr, Washington, DC 20007 USA
Anand, Aashish
Rao, Anantha K.
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Medstar Georgetown Univ, Washington Hosp Ctr, Intervent Cardiol, Washington, DC 20007 USAMedstar Georgetown Univ, Washington Hosp Ctr, Washington, DC 20007 USA