Phosphodiesterase 3A modulators sensitize tumor cells to Bcl-2/Bcl-xL inhibitors

被引：0
|
作者：
Toivanen, Kirsi L. J.
Murumagi, Astrid
Arjama, Mariliina A.
Merikoski, Nanna J.
Salmikangas, Sami I.
Kallioniemi, Olli P.
Bohling, Tom O.
Sihto, Harri J.
机构：
来源：
MOLECULAR CANCER THERAPEUTICS | 2023年 / 22卷 / 12期
关键词：
D O I：
10.1158/1535-7163.TARG-23-B028
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
B028
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Modulation of synaptic transmission by the BCL-2 family protein BCL-xL
    Jonas, EA
    Hoit, D
    Hickman, JA
    Brandt, TA
    Polster, BM
    Fannjiang, Y
    McCarthy, E
    Montanez, MK
    Hardwick, JM
    Kaczmarek, LK
    [J]. JOURNAL OF NEUROSCIENCE, 2003, 23 (23): : 8423 - 8431
  • [32] Bcl-2/Bcl-xL inhibitor navitoclax increases the antitumor effect of Chk1 inhibitor prexasertib by inducing apoptosis in pancreatic cancer cells via inhibition of Bcl-xL but not Bcl-2
    Yoshihito Morimoto
    Kimihiko Takada
    Osamu Takeuchi
    Kazuhiro Watanabe
    Masayoshi Hirohara
    Tomoyuki Hamamoto
    Yutaka Masuda
    [J]. Molecular and Cellular Biochemistry, 2020, 472 : 187 - 198
  • [33] Imaging of Bcl-2/Bcl-xL dysregulated apoptotic program in NSCLC cells resistant to EGFR tyrosine kinase inhibitors
    Zannetti, A.
    Iommelli, F.
    Fonti, R.
    Lettieri, A.
    Pirozzi, G.
    Bianco, R.
    Tortora, G.
    Salvatore, M.
    Del Vecchio, S.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2009, 36 : S476 - S476
  • [34] Bcl-2/Bcl-xL inhibitor navitoclax increases the antitumor effect of Chk1 inhibitor prexasertib by inducing apoptosis in pancreatic cancer cells via inhibition of Bcl-xL but not Bcl-2
    Morimoto, Yoshihito
    Takada, Kimihiko
    Takeuchi, Osamu
    Watanabe, Kazuhiro
    Hirohara, Masayoshi
    Hamamoto, Tomoyuki
    Masuda, Yutaka
    [J]. MOLECULAR AND CELLULAR BIOCHEMISTRY, 2020, 472 (1-2) : 187 - 198
  • [35] Bcl-2 and Bcl-xL are important for the induction of paclitaxel resistance in human hepatocellular carcinoma cells
    Chun, EY
    Lee, KY
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 315 (03) : 771 - 779
  • [36] Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity
    Donatella Del Bufalo
    Daniela Trisciuoglio
    Marco Scarsella
    Uwe Zangemeister-Wittke
    Gabriella Zupi
    [J]. Oncogene, 2003, 22 : 8441 - 8447
  • [37] Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity
    Del Bufalo, D
    Trisciuoglio, D
    Scarsella, M
    Zangemeister-Wittke, U
    Zupi, G
    [J]. ONCOGENE, 2003, 22 (52) : 8441 - 8447
  • [38] Redefining Cancer Therapy: Toward BCL-XL/BCL-2 Dual Inhibitors with Diminished Platelet Toxicity
    Kargbo, Robert B.
    [J]. ACS MEDICINAL CHEMISTRY LETTERS, 2023, 14 (09): : 1156 - 1158
  • [39] Unidirectional crosstalk between Bcl-xL and Bcl-2 enhances the angiogenic phenotype of endothelial cells
    Karl, E.
    Zhang, Z.
    Dong, Z.
    Neiva, K. G.
    Soengas, M. S.
    Koch, A. E.
    Polverini, P. J.
    Nunez, G.
    Noer, J. E.
    [J]. CELL DEATH AND DIFFERENTIATION, 2007, 14 (09): : 1657 - 1666
  • [40] Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL
    Inohara, N
    Ekhterae, D
    Garcia, I
    Carrio, R
    Merino, J
    Merry, A
    Chen, S
    Núñez, G
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (15) : 8705 - 8710
12345