Of mice, or men: TLR4 signaling in HIV pathogenesis

被引：1
|
作者：
Acosta, Reyes [1 ,2 ]
Claiborne, Daniel T. [2 ,3 ]
机构：
[1] Univ Penn, Perelman Sch Med, Dept Microbiol, 3451 Walnut St, Philadelphia, PA 19104 USA
[2] Wistar Inst Anat & Biol, Vaccine & Immunotherapy Ctr, 3601 Spruce St, Philadelphia, PA 19104 USA
[3] Wistar Inst Anat & Biol, 3601 Spruce St, Philadelphia, PA 19104 USA
来源：
JOURNAL OF LEUKOCYTE BIOLOGY | 2023年 / 113卷 / 05期
关键词：
MICROBIAL TRANSLOCATION; IMMUNE ACTIVATION; INFECTION;
D O I：
10.1093/jleuko/qiad017
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
A murine Tlr4null humanized mouse model offers a new tool to study mechanisms by which microbial translocation affects adaptive immune function and exacerbates HIV-1 pathogenesis.
引用
收藏
页码：415 / 417
页数：3
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