Sulfur(vi) fluorides as tools in biomolecular and medicinal chemistry

被引：43

作者：

Carneiro, Sabrina N. ^{[1
]}

Khasnavis, Samuel R. ^{[1
]}

Lee, Jisun ^{[2
]}

Butler, Todd W. ^{[2
]}

Majmudar, Jaimeen D. ^{[3
]}

Am Ende, Christopher W. ^{[2
]}

Ball, Nicholas D. ^{[1
]}

机构：

[1] Pomona Coll, Dept Chem, Claremont, CA 91711 USA

[2] Pfizer Worldwide Res, Dev, Groton, CT 06340 USA

[3] Pfizer Worldwide Res & Dev, Cambridge, MA 02139 USA

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2023年 / 21卷 / 07期

基金：

美国国家卫生研究院;

关键词：

SUFEX CLICK CHEMISTRY; AROMATIC SULFONYL FLUORIDES; PORCINE PANCREATIC ELASTASE; IRREVERSIBLE INHIBITORS; CATHEPSIN-G; REACTIVITY; SITE; FLUOROSULFATE; CHYMOTRYPSIN; CONVENIENT;

D O I：

10.1039/d2ob01891h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Recent advances in the synthesis of sulfur(vi)-fluorides has enabled incredible growth in their application in biomolecular chemistry. This review aims to serve as a primer highlighting synthetic strategies toward a diversity of S(vi) fluorides and their application in chemical biology, bioconjugation, and medicinal chemistry.

引用

页码：1356 / 1372

页数：17

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