Photonic Si microwell architectures for rapid antifungal susceptibility determination of Candida auris

被引：0
|
作者：
Heuer, Christopher [1 ,2 ,3 ]
Jiang, Xin [1 ]
Ron, Gali [1 ]
Ternyak, Orna [4 ]
Scheper, Thomas [2 ]
Bahnemann, Janina [3 ]
Segal, Ester [1 ]
机构：
[1] Technion Israel Inst Technol, Dept Biotechnol & Food Engn, IL-3200003 Haifa, Israel
[2] Leibniz Univ Hannover, Inst Tech Chem, D-30167 Hannover, Germany
[3] Univ Augsburg, Inst Phys, D-86159 Augsburg, Germany
[4] Technion Israel Inst Technol, Microand Nanofabricat & Printing Unit, IL-3200003 Haifa, Israel
来源：
CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 10期
基金：
以色列科学基金会;
关键词：
CLSI BROTH MICRODILUTION; VITEK; 2;
D O I：
10.1039/d3cc04446g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We present the application of a photonic silicon chip-based optical sensor system for expeditious and phenotypic antifungal susceptibility testing. This label-free diagnostic assay optically monitors the growth of Candida auris at varying antifungal concentrations on a microwell-structured silicon chip in real-time, and antifungal susceptibility is detected within 6 h, four times faster than in the current gold standard method.
引用
收藏
页码：1305 / 1308
页数：4
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