Evaluation of antioxidant and cytotoxicity activities of polyphenol extracted from brown seaweed Sargassum tenerrimum biomass

被引：8
|
作者：
Mahendran, Shunmugiah [1 ]
Sankaralingam, Subbiah [2 ]
Sethupathi, Senthurpandian Muthuramalinga [1 ]
Kathiresan, Durairaj [2 ]
Muthumani, Mahalingam [2 ]
Kousalya, Loganathan [3 ]
Palpperumal, Selvam [4 ]
Harinathan, Balasundaram [4 ]
机构：
[1] Ayya Nadar Janaki Ammal Coll Autonomous, Dept Microbiol, Sivakasi, Tamil Nadu, India
[2] Saraswathi Narayanan Coll, PG & Res Dept Bot, Madurai 22, Tamil Nadu, India
[3] Nirmala Coll Women, Dept Bot, Coimbatore 641018, Tamil Nadu, India
[4] VHN Senthikumara Nadar Coll, PG & Res Dept Microbiol, Virudunagar, Tamil Nadu, India
来源：
BIOMASS CONVERSION AND BIOREFINERY | 2024年 / 14卷 / 02期
关键词：
Polyphenol; Phytochemical; Cytotoxicity; HPLC; PHENOLIC-COMPOUNDS; ANTIBACTERIAL; PLANT; DIET;
D O I：
10.1007/s13399-022-02301-x
中图分类号：
TE [石油、天然气工业]; TK [能源与动力工程];
学科分类号：
0807 ; 0820 ;
摘要：
The polyphenol compound is extracted from Sargassum tenerrimum with various bioactivities including antibacterial and antioxidant activity and MTT assay for cell cytotoxicity. The total phenolic content was 69.12 +/- 0.24%. The S. tenerrimum polyphenol was found to phytochemical constituent's presence of flavonoids, saponins, tannins, phenolics, alkaloids and steroid. The antibacterial activity of polyphenol presented significant inhibition against ten human pathogen bacterial cultures such as Proteus mirabilis, Klebsiella oxytoca, Escherichia coli, Bacillus cereus, Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa, Vibrio cholerae, Salmonella typhi and Bacillus subtilis. The in vitro antioxidant activity and MTT assay revealed that the polyphenol has anticancer activity against HeLa cells. The polyphenol compound was characterized through HPLC.
引用
收藏
页码：2063 / 2069
页数：7
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