Evaluation of radiation dose and radiation-induced cancer risk associated with routine CT scan examinations

被引:0
|
作者
Bagherzadeh, Saeed [1 ]
Mirderikvand, Afsaneh [2 ]
Mohammadsharifi, Ali [3 ]
机构
[1] Tarbiat Modares Univ, Fac Med, Dept Med Phys, Tehran, Iran
[2] Kermanshah Univ Med Sci, Dept Med Phys, Kermanshah, Iran
[3] Shahid Beheshti Univ Med Sci, Shahid Modarres Educ Hosp, Clin Res Dev Ctr, Tehran, Iran
关键词
Computed tomography; Radiation dose; Cancer incidence; Cancer mortality; BEIR VII; COMPUTED-TOMOGRAPHY EXAMINATIONS; EXPOSURE; PROTECTION; ORGANS; LENS;
D O I
10.1016/j.radphyschem.2024.111521
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Using patient -specific data, the present study aimed to identify organ and effective dose to estimate the lifetime attributable risks (LARs) of cancer incidence and mortality associated with routine CT procedures. A crosssectional investigation was conducted on 515 patients who underwent CT scan. The effective dose was computed using two methods: first, the ImPACT software and relevant conversion factors. Second, the effective dose was determined using the scanner -derived DLP and AAPM TG 23's conversion factor. Using the biological effects of ionizing radiation (BEIR VII) report, LAR of cancer incidence and mortality were computed. The greatest mean organ doses for abdomen -pelvis, routine chest, chest HRCT, brain, and sinus examinations were 20.64 +/- 3.27 mGy (kidneys), 21.55 +/- 5.47 mGy (thymus and esophagus), 10.51 +/- 1.31 mGy (thymus and esophagus), 22.72 +/- 3.01 mGy (lens), and 18.56 +/- 1.25 mGy (lens) respectively. Using ImPACT dosimetry software, the mean effective dose for routine chest, abdomen -pelvis, HRCT chest, brain, and sinus examinations was 8.46 mSv, 10.13 mSv, 4.19 mSv, 1 mSv, and 0.68 mSv, respectively. Using the DLP to effective dose conversion factor, the mean effective dose was lower. The mean cancer incidence risks per 100,000 people were 63.33, 54.98, 27.82, 6.31, and 5.22 for abdomen -pelvis, routine chest, HRCT, brain, and sinus examinations, respectively. The mean LAR of cancer mortality for all cancer was 38.22, 33.17, 16.72, 3.87, 2.93 for abdomenpelvis, routine chest, HRCT, brain, and sinus examinations, respectively, per 100,000 people. Thus, CT scan exams are connected with a non -negligible risk of cancer, and patient radiation dose must be optimized to limit radiation risk.
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页数:7
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