Synthesis of New Thiazolidinones and Thiazoles in Indole Series

被引：3
|
作者：
Khanoussi, Sofiane [1 ]
Benmohammed, Abdelmadjid [1 ,2 ]
Khoumeri, Omar [3 ]
Kadiri, Mokhtaria [1 ]
Djafri, Ayada [1 ]
Terme, Thierry [3 ]
Vanelle, Patrice [3 ]
机构：
[1] Univ Oran1 Ahmed Ben Bella, Fac Sci Exactes & Appl, Dept Chim, Lab Synth Organ Appliquee LSOA, BP 1524 MNaouer, Oran 31000, Algeria
[2] Univ Mascara, Fac Exact Sci, Dept Chem, Mascara 29000, Algeria
[3] Aix Marseille Univ, ICR Inst Chim Radicalaire, Fac Pharm, Lab Pharmaco Chim Radicalaire,CNRS,UMR 7273, 27 Blvd Jean Moulin, F-13385 Marseille 05, France
来源：
LETTERS IN ORGANIC CHEMISTRY | 2023年 / 20卷 / 01期
关键词：
Thiosemicarbazone; thiazolidinone; thiazole; indole; condensation; cyclization; BIOLOGICAL EVALUATION; THIOSEMICARBAZONE DERIVATIVES; AGENTS; ANTIOXIDANT; ANTICONVULSANT; COMPLEXES; DOCKING; DESIGN;
D O I：
10.2174/1570178619666220827152700
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Recent findings confirm that thiosemicarbazones and thiazoles offer a wide range of biological properties. We report here the synthesis of two series of highly functionalized thiazole-derived compounds from the reactions of various indole-derived thiosemicarbazones with diethyl acetylenedicarboxylate and 4-bromophenacyl bromide. As a result, a series of new derivatives of thiosemicarbazone, thiazolidinone, and thiazole bearing an indole moiety was synthesized and developed in good yields.
引用
收藏
页码：11 / 17
页数：7
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