Recent advances in discovery and biosynthesis of natural products from myxobacteria: an overview from 2017 to 2023

被引：4
|
作者：
Wang, Chao-Yi [1 ]
Hu, Jia-Qi [1 ]
Wang, De-Gao [1 ]
Li, Yue-Zhong [1 ]
Wu, Changsheng [1 ]
机构：
[1] Shandong Univ, Inst Microbial Technol, State Key Lab Microbial Technol, Qingdao 266237, Peoples R China
来源：
NATURAL PRODUCT REPORTS | 2024年 / 41卷 / 06期
基金：
中国国家自然科学基金;
关键词：
ANTIMICROBIAL CYCLIC DEPSIPEPTIDES; IN-VITRO RECONSTITUTION; GENOME-GUIDED DISCOVERY; MYXOCOCCUS-XANTHUS; HETEROLOGOUS PRODUCTION; GLIDING BACTERIA; GENE-CLUSTER; STIGMATELLA-AURANTIACA; SECONDARY METABOLITES; STRUCTURE ELUCIDATION;
D O I：
10.1039/d3np00062a
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Covering: 2017.01 to 2023.11Natural products biosynthesized by myxobacteria are appealing due to their sophisticated chemical skeletons, remarkable biological activities, and intriguing biosynthetic enzymology. This review aims to systematically summarize the advances in the discovery methods, new structures, and bioactivities of myxobacterial NPs reported in the period of 2017-2023. In addition, the peculiar biosynthetic pathways of several structural families are also highlighted. This review presents a comprehensive overview of recent advances in the discovery methodologies, new structures, bioactivities, and unique biosynthetic logics of myxobacterial natural products reported from January 2017 to November 2023.
引用
收藏
页码：905 / 934
页数：30
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