Use and Prognostic Implications of Cardiac Troponin in COVID-19

Myocardial injury, defined as cTn increases above the assay-specific 99th percentile, is frequent in patients with COVID-19. It correlates with adverse events and short-term mortality. Most increases seem related to chronic cardiovascular conditions and acute nonischemic myocardial injury, similarly to that reported in severely ill patients. However, some studies with advanced cardiac imaging and long-term follow-up indicate that myocardial injury might be associated with long-term struc-tural abnormalities and worse cardiac perfor-mance. Except for patients suffering from type 1 MI, the appropriate treatment of patients with COVID-19 with myocardial injury remains case -specific and further investigations are necessary to understand how to improve outcomes in this population.