A comprehensive review on phytochemistry, bioactivity and medicinal value of bioactive compounds of pomegranate (Punica granatum)

被引:50
|
作者
Ranjha, Muhammad Modassar Ali Nawaz [1 ]
Shafique, Bakhtawar [1 ]
Wang, Lufeng [2 ]
Irfan, Shafeeqa [1 ]
Safdar, Muhammad Naeem [3 ]
Murtaza, Mian Anjum [1 ]
Nadeem, Muhammad [1 ]
Mahmood, Shahid [1 ]
Mueen-ud-Din, Ghulam [1 ]
Nadeem, Hafiz Rehan [4 ]
机构
[1] Univ Sargodha, Inst Food Sci & Nutr, Sargodha 40100, Pakistan
[2] Huazhong Agr Univ, Coll Food Sci & Technol, Wuhan, Hubei, Peoples R China
[3] Natl Agr Res Ctr, Food Sci Res Inst, Islamabad, Pakistan
[4] Bahauddin Zakariya Univ, Inst Food Sci & Nutr, Multan, Pakistan
关键词
Pomegranate; Phytochemistry; Bioavailability and Bioactivity; Medicinal uses; Bioactive compounds; Polyphenols; OXIDATIVE STRESS; ANTIOXIDANT PROPERTIES; IN-VITRO; MOLECULAR-MECHANISMS; BLOOD-PRESSURE; FRUIT EXTRACT; PEEL EXTRACT; SEED OIL; JUICE; RUTIN;
D O I
10.1007/s13596-021-00566-7
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Pomegranate (Punica granatum) acts as a therapeutic fruit possessing different bioactive compounds. Different compartments of pomegranate (P. granatum) like seed, peel, juice and leaves are rich in potential bioactive compounds. Pomegranate contains sinapyl, coniferyl, ellagic acid, cinnamic acid, genistein, linoleic acid, anthocyanin, gallic acid, catechin, quercetin, rutin, kaempferol, cyanidin, punicalin, delphinidin, punicalagin, chlorogenic acid, coumaric acid, luteolin and pelletierine alkaloids, flavonoids, anthocyanin and caffeic acid. Pomegranate also exhibits significant anti-oxidative, anti-hypertensive, cardioprotective and anti-diabetic properties and anti-carcinogenic possessions including prevention of prostate cancer; reduction in colon inflammation, prevention of skin tumorigenesis, improvement in renal function and reduction in metastatic melanoma growth. This review summarizes the current available data on the phytochemistry, bioavailability and therapeutic importance of potential bioactive compounds of pomegranate.
引用
收藏
页码:37 / 57
页数:21
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