Multiple Myeloma Treatment Guidelines by the Portuguese Group of Multiple Myeloma

被引：0

作者：

Joao, Cristina ^{[1
,2
]}

Bergantim, Rui ^{[3
,4
,5
]}

Santos, Joana ^{[6
]}

Afonso, Celina ^{[7
]}

Bernardo, Paulo ^{[8
]}

Coelho, Henrique ^{[9
]}

Costa, Carlos ^{[10
]}

Esteves, Graca ^{[11
]}

Freitas, Jose Guilherme ^{[12
]}

Gerivaz, Rita ^{[13
]}

Jorge, Ana ^{[7
]}

Macedo, Ana ^{[14
,15
]}

Montalvao, Ana ^{[16
,17
]}

Neves, Manuel ^{[1
]}

Pedrosa, Claudia L. ^{[18
]}

Pereira, Susana ^{[19
]}

Roque, Adriana ^{[20
,21
]}

Seabra, Patricia ^{[18
]}

Silva, Helena M. ^{[22
]}

Silveira, Maria P. ^{[23
,24
]}

Tome, Ana ^{[13
]}

Trigo, Fernanda ^{[3
]}

Sarmento, Ana Bela ^{[20
,25
,26
,27
]}

Lucio, Paulo ^{[1
]}

Geraldes, Catarina ^{[20
,25
,26
,27
]}

机构：

[1] Fundacao Champalimaud, Serv Hematooncol, Lisbon, Portugal

[2] Univ Nova Lisboa, NOVA Med Sch, Lisbon, Portugal

[3] Ctr Hosp Sao Joao, Serv Hematol, Porto, Portugal

[4] Univ Porto, I3S Inst Invest & Inovacao Saude, Porto, Portugal

[5] Univ Porto, Canc Drug Resistance Grp, IPATIMUP Inst Patol Mol & Imunol, Porto, Portugal

[6] Ctr Hosp Lisboa Central, Serv Hematol, Lisbon, Portugal

[7] Ctr Hosp Lisboa Ocidental, Serv Hematol Clin, Lisbon, Portugal

[8] Hosp Luz Lisboa, Serv Hematol Clin, Lisbon, Portugal

[9] Ctr Hosp Vila Nova Gaia, Serv Hematol Clin, Gaia, Portugal

[10] Inst CUF Oncol, Hematol Clin, Lisbon, Portugal

[11] Ctr Hosp Univ Lisboa Norte, Serv Hematol & Transplante Medula, Lisbon, Portugal

[12] Inst Portugues Oncol Porto, Serv Oncohematol, Porto, Portugal

[13] Hosp Garcia Orta, Serv Hematol, Almada, Portugal

[14] Ctr Hosp Univ Algarve, Serv Hematol, Algarve, Portugal

[15] Univ Beira Interior, Fac Ciencias Saude, Covilha, Portugal

[16] Unidade Local Saude Baixo Alentejo, Unidade Hematol Oncol, Beja, Portugal

[17] Hosp Jose Joaquim Fernandes, Beja, Portugal

[18] Ctr Hosp Univ Porto, Serv Hematol Clin, Porto, Portugal

[19] Ctr Hosp Univ Lisboa Central, Serv Hematol, Hosp Santo Antonio Capuchos, Lisbon, Portugal

[20] Ctr Hosp & Univ Coimbra, Serv Hematol Clin, Coimbra, Portugal

[21] Univ Coimbra, Fac Med, Inst Fisiol, Coimbra, Portugal

[22] Ctr Hosp Tondela Viseu, Serv Hematol, Viseu, Portugal

[23] Ctr Clin SAMS, Hematologia Clin, Clin Oncol & Radioterapia, Lisbon, Portugal

[24] Hosp Prof Doutor Fernando Fonseca, Serv Imunohemoterapia, Amadora, Portugal

[25] Univ Coimbra, Fac Med, Clin Univ Hematol, Lab Oncobiol & Hematol, Coimbra, Portugal

[26] Univ Coimbra, Fac Med, Inst Invest Clin & Biomed Coimbra, Grp Invest Ambiente Genet & Oncobiol, Coimbra, Portugal

[27] Ctr Acad Clin Coimbra, Coimbra, Portugal

来源：

ACTA MEDICA PORTUGUESA | 2023年 / 36卷 / 7-8期

关键词：

Multiple Myeloma; drug therapy; Portugal; STEM-CELL TRANSPLANTATION; OPEN-LABEL; LENALIDOMIDE MAINTENANCE; INDUCTION TREATMENT; PATIENT OUTCOMES; ORAL IXAZOMIB; BORTEZOMIB; DEXAMETHASONE; THERAPY; SURVIVAL;

D O I：

10.20344/amp.19037

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The treatment of multiple myeloma has profoundly changed with the introduction of several innovative therapies. The optimization of therapeutic sequencing through the combined use of the various drugs developed in recent years and the attention given to the characteristics of patients have allowed the reduction of toxicities and increased survival and quality of life of patients with multiple myeloma. These treatment recommendations from the Portuguese Multiple Myeloma Group offer guidance for first-line treatment and progression/relapse situations. These recommendations are given highlighting the data that justify each choice and referring to the respective levels of evidence that support these options. Whenever possible, the respective national regulatory framework is presented. These recommendations constitute an advance towards the best treatment of multiple myeloma in Portugal.

引用

页码：517 / 526

页数：10

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