Hairy Root Cultures as a Source of Phenolic Antioxidants: Simple Phenolics, Phenolic Acids, Phenylethanoids, and Hydroxycinnamates

被引:8
|
作者
Malarz, Janusz [1 ]
Yudina, Yulia V. [2 ]
Stojakowska, Anna [1 ]
机构
[1] Polish Acad Sci, Maj Inst Pharmacol, Smetna St 12, PL-31343 Krakow, Poland
[2] Natl Tech Univ, Educ & Sci Med Inst, Kharkiv Polytech Inst, Kyrpychova St 2, UA-61002 Kharkiv, Ukraine
关键词
Agrobacterium rhizogenes; caffeoylquinic acid; chlorogenic acid; chicoric acid; phenolic acid; salvianolic acid; Rhizobium rhizogenes; rosmarinic acid; salidroside; verbascoside; RHIZOGENES-MEDIATED TRANSFORMATION; SECONDARY METABOLITE PRODUCTION; P-HYDROXYBENZOIC ACID; ACYL-QUINIC ACIDS; IN-VITRO CULTURES; ROSMARINIC ACID; CHLOROGENIC ACID; AGROBACTERIUM-RHIZOGENES; METHYL JASMONATE; CHICORIC ACID;
D O I
10.3390/ijms24086920
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Plant-derived antioxidants are intrinsic components of human diet and factors implicated in tolerance mechanisms against environmental stresses in both plants and humans. They are being used as food preservatives and additives or ingredients of cosmetics. For nearly forty years, Rhizobium rhizogenes-transformed roots (hairy roots) have been studied in respect to their usability as producers of plant specialized metabolites of different, primarily medical applications. Moreover, the hairy root cultures have proven their value as a tool in crop plant improvement and in plant secondary metabolism investigations. Though cultivated plants remain a major source of plant polyphenolics of economic importance, the decline in biodiversity caused by climate changes and overexploitation of natural resources may increase the interest in hairy roots as a productive and renewable source of biologically active compounds. The present review examines hairy roots as efficient producers of simple phenolics, phenylethanoids, and hydroxycinnamates of plant origin and summarizes efforts to maximize the product yield. Attempts to use Rhizobium rhizogenes-mediated genetic transformation for inducing enhanced production of the plant phenolics/polyphenolics in crop plants are also mentioned.
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页数:29
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