Thromboembolic complications after COVID-19 in kidney transplant recipients

被引:0
|
作者
Artan, Ayse Serra [1 ]
Dirim, Ahmet Burak [2 ]
Yavuzkilic, Halil [1 ]
Demir, Erol [3 ]
Oto, Ozgur Akin [1 ]
Guller, Nurana [1 ]
Safak, Seda [1 ]
Yazici, Halil [1 ]
Turkmen, Aydin [1 ]
机构
[1] Istanbul Univ, Istanbul Fac Med, Dept Internal Med, Div Nephrol, TR-34093 Istanbul, Turkiye
[2] Sanliurfa Training & Res Hosp, Istanbul, Turkiye
[3] Koc Univ, Koc Univ Hosp, Transplant Immunol Res Ctr Excellence, Istanbul, Turkiye
关键词
COVID-19; kidney transplantation; thromboembolism; HOSPITALIZED-PATIENTS; EVENTS;
D O I
10.1111/nep.14242
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Aim: Increased venous thrombosis and arterial embolism rates are observed in the general population during or after COVID-19. Data regarding the kidney transplant population are scarce. In this study, we aim to investigate the thrombotic complications and risk factors associated with thrombotic complications in kidney transplant patients.Methods: This retrospective observational study included adult kidney transplant recipients diagnosed with COVID-19 between March 2020 and June 2022. The endpoint was the occurrence of thromboembolic events.Results: Four hundred and sixty-nine patients were followed for a median of 10.8 months after COVID-19. Forty patients (8.5%) died. Thromboembolic complications developed in 51 (11.9%) of the surviving patients. Twenty-four patients with thromboembolic events were receiving prophylactic anticoagulation before the event. The patients with mild, moderate, and severe COVID-19 were 292, 129, and 48, respectively. Patients with moderate COVID-19 had a significantly higher percentage of thromboembolic complications than patients with mild COVID-19. Older age, prior heart disease, and moderate COVID-19 were significantly associated with thromboembolic events. The incidence of thromboembolic events after COVID-19 is 10.9 per 100 patient-year.Conclusion: Thromboembolic complications were observed at increased rates in kidney transplant recipients after COVID-19. Therefore, prospective and cohort studies for post-COVID-19 complications regarding the treatment modalities are urgently needed.
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页码:39 / 47
页数:9
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