Three new chromanes and one new flavone C-glycoside from Mallotus apelta

被引：4

作者：

Nguyen Hoang Anh ^{[1
,2
]}

Duong Thi Hai Yen ^{[3
]}

Nguyen The Cuong ^{[4
]}

Bui Huu Tai ^{[1
,3
]}

Pham Hai Yen ^{[1
]}

Pham The Chinh ^{[2
]}

Pham Van Cuong ^{[3
]}

Nguyen Hoai Nam ^{[3
]}

Phan Van Kiem ^{[1
,3
]}

Su-Hyeon Cho ^{[5
]}

Park, SeonJu ^{[5
]}

Nguyen Xuan Nhiem ^{[1
,3
]}

机构：

[1] Vietnam Acad Sci & Technol VAST, Grad Univ Sci & Technol, Hanoi 10072, Vietnam

[2] Thai Nguyen Univ Sci, Fac Chem, Thai Nguyen 24118, Vietnam

[3] VAST, Inst Marine Biochem, 18 Hoang Quoc Viet, Hanoi 10072, Vietnam

[4] VAST, Inst Ecol & Biol Resources, Hanoi 10072, Vietnam

[5] Korea Basic Sci Inst, Chuncheon Ctr, 1 Kangwondaehak Gil, Chuncheon Si 24341, Gangwon Do, South Korea

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2023年 / 25卷 / 01期

关键词：

Mallotus apelta; Euphorbiaceae; chromane; flavone C-glycoside; malloapelta; malloflavoside;

D O I：

10.1080/10286020.2022.2051494

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new chromanes, malloapeltas J-L (1-3), and one new flavone C-glycoside, malloflavoside (4), together with four known compounds, apigenin 6-C-beta-D-xylopyranosyl-8-C-alpha-L-arabinopyranoside (5), apigenin 6-C-beta-D-glucopyranosyl-8-C-alpha-L-arabinopyranoside (6), apigenin 7-O-beta-D-apiofuranosyl-(1 -> 2)-beta-D-glucopyranoside (7), and acantrifoside E (8) were isolated from the methanol extract of the leaves of Mallotus apelta. Their chemical structures were determined using spectroscopic methods, including 1D, 2D NMR, and HR-ESI-MS methods. All the isolated compounds were evaluated their cytotoxic activity against human prostate cancer (PC-3) and human breast cancer (MCF-7) cells, but none of them showed cytotoxicities on both human cancer cell lines.

引用

页码：18 / 26

页数：9

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