The dose-response of direct oral anticoagulants is non-linear at plasma levels below 100 ng/ml

被引:1
|
作者
Metze, Michael [1 ]
Siegemund, Annelie [2 ]
Siegemund, Thomas [2 ]
Kloeter, Tristan [1 ]
Stoebe, Stephan [1 ]
Laufs, Ulrich [1 ]
Petros, Sirak [1 ,2 ,3 ]
Pfrepper, Christian [3 ]
机构
[1] Univ Hosp Leipzig, Dept Cardiol, Med Dept 4, Leipzig, Germany
[2] Univ Hosp Leipzig, Med ICU, Leipzig, Germany
[3] Univ Hosp Leipzig, Div Hemostaseol, Med Dept 1, Leipzig, Germany
关键词
APIXABAN;
D O I
10.1111/ijlh.14004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:e60 / e63
页数:4
相关论文
共 50 条
  • [31] Identification of non-linear influences on the seasonal ozone dose-response of sensitive and resistant clover clones using artificial neural networks
    Ball, GR
    Palmer-Brown, D
    Fuhrer, J
    Skärby, L
    Gimeno, BS
    Mills, G
    ECOLOGICAL MODELLING, 2000, 129 (2-3) : 153 - 168
  • [32] EPINEPHRINE-INDUCED ARRHYTHMIAS DURING ENFLURANE ANESTHESIA IN MAN - NON-LINEAR DOSE-RESPONSE RELATIONSHIP AND DOSE-DEPENDENT PROTECTION FROM LIDOCAINE
    HORRIGAN, RW
    EGER, EI
    WILSON, C
    ANESTHESIA AND ANALGESIA, 1978, 57 (05): : 547 - 550
  • [33] THE ROLE OF LINEAR AND NON-LINEAR DOSE-RESPONSE MODELS IN PUBLIC DECISION-MAKING (WHAT TO DO WHEN UNCERTAINTY AFFECTS ENVIRONMENTAL HEALTH CHOICES)
    Ricci, P. F.
    Sammis, Ian R.
    DOSE-RESPONSE, 2012, 10 (02): : 203 - 208
  • [34] Workshop report: Identifying key issues underpinning the selection of linear or non-linear dose-response extrapolation for human health risk assessment of systemic toxicants
    Pottenger, Lynn H.
    Becker, Richard A.
    Moran, Elizabeth J.
    Swenberg, James A.
    REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2011, 59 (03) : 503 - 510
  • [35] LINEAR VERSUS NON-LINEAR DOSE-RESPONSE RELATIONSHIP BETWEEN PRENATAL ALCOHOL EXPOSURE AND MECONIUM CONCENTRATION OF NINE DIFFERENT FATTY ACID ETHYL ESTERS
    Yang, J. Y.
    Kwak, H. S.
    Han, J. Y.
    Choi, J. S.
    Ahn, H. K.
    Oh, Y. J.
    Velazquez-Armenta, E. Y.
    Nava-Ocampo, A. A.
    DOSE-RESPONSE, 2015, 13 (01): : 1 - 12
  • [36] Inappropriate low dosing of direct oral anticoagulants in older patients with non-valvular atrial fibrillation: Impact on plasma drug levels
    Comans, Anne-Lore
    Sennesael, Anne-Laure
    Bihin, Benoit
    Regnier, Maxime
    Mullier, Francois
    Saint-Hubert, Marie de
    THROMBOSIS RESEARCH, 2021, 201 : 139 - 142
  • [37] Dairy intake and risk of hip fracture in prospective cohort studies: non-linear algorithmic dose-response analysis in 486 950 adults
    Mishra, Suruchi
    Baruah, Kavitha
    Malik, Vasanti S.
    Ding, Eric L.
    JOURNAL OF NUTRITIONAL SCIENCE, 2023, 12
  • [38] Association between total sleep time and all cancer mortality: non-linear dose-response meta-analysis of cohort studies
    Li, Yingjun
    Cai, Shaofang
    Ling, Yuxiao
    Mi, Shuai
    Fan, Chunhong
    Zhong, Yaohong
    Shen, Qing
    SLEEP MEDICINE, 2019, 60 : 211 - 218
  • [39] Non-Linear Relationship between Recipient BMI and Survival Outcomes after Liver Transplantation-A Dose-Response Meta-Analysis
    Song, T.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2020, 20 : 1114 - 1114
  • [40] Another fundamental error in "What is the meaning of non-linear dose-response relationships between blood lead concentrations and IQ?" became obvious in the authors' response to comments
    Bergdahl, Ingvar A.
    NEUROTOXICOLOGY, 2007, 28 (03) : 705 - 706