Synthesis, characterization, antibacterial and anticancer activities of some heterocyclic imine compounds

被引：11

作者：

Bsharat, Inas ^{[1
]}

Abdalla, Lubna ^{[2
]}

Sawafta, Ashraf ^{[2
]}

Abu-Reidah, Ibrahim M. ^{[3
]}

Al-Nuri, Mohammed A. ^{[1
]}

机构：

[1] An Najah Natl Univ, Sci Coll, Dept Chem, POB 7, Nablus, Palestine

[2] An Najah Natl Univ, Biol & Biotechnol Dept, POB 7, Nablus, Palestine

[3] Mem Univ Newfoundland, Core Sci Facil, St John, NF A1C 5S7, Canada

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2023年 / 1289卷

关键词：

Schiff bases; Imines; Anticancer; Antibacterial; SCHIFF-BASE COMPLEXES; TRANSITION-METAL-COMPLEXES; BIOLOGICAL-ACTIVITY; CARBENE COMPLEXES; CRYSTAL-STRUCTURE; SENSOR; SILVER; CELLS; GOLD; DFT;

D O I：

10.1016/j.molstruc.2023.135789

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Schiff Base compounds are among the most important organic compounds that have an important role in the medical field due to their various biological properties. In this work, four new imine compounds (3, 4, 7 and 8) were synthesized in dichloromethane at room temperature from two heterocyclic aromatic aldehydes and three compounds of primary amines. The new compounds were identified by FTIR, 1H and 13C NMR analysis. In 1H-NMR the hydrogen of imine bonds was observed at 8.02-8.3 ppm and the carbon of imine bonds was observed at 153.82-164.89 ppm. Also, C=N double bond was observed around 1650 cm-1 in FTIR spectra. All compounds were tested for their antibacterial as well as anticancer activities.

引用

页数：9

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