The role of sialidase Neu1 in respiratory diseases

被引：3
|
作者：
Mei, Shiran [1 ]
Li, Dingding [1 ]
Wang, Aoyi [1 ]
Zhu, Guoxue [1 ]
Zhou, Bingwen [1 ]
Li, Nian [1 ]
Qin, Yi [1 ]
Zhang, Yanliang [1 ,2 ]
Jiang, Shujun [1 ,2 ]
机构：
[1] Nanjing Univ Chinese Med, Nanjing Hosp Chinese Med, Nanjing, Peoples R China
[2] Nanjing Res Ctr Infect Dis Integrated Tradit Chine, Nanjing, Jiangsu, Peoples R China
来源：
RESPIRATORY RESEARCH | 2024年 / 25卷 / 01期
关键词：
IDIOPATHIC PULMONARY-FIBROSIS; SELECTIVE INHIBITORS; HUMAN NEURAMINIDASE; LYSOSOMAL SIALIDASE; T-LYMPHOCYTES; LUNG-CANCER; EXPRESSION; RECEPTOR; CD44; DIFFERENTIATION;
D O I：
10.1186/s12931-024-02763-9
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Neu1 is a sialidase enzyme that plays a crucial role in the regulation of glycosylation in a variety of cellular processes, including cellular signaling and inflammation. In recent years, numerous evidence has suggested that human NEU1 is also involved in the pathogenesis of various respiratory diseases, including lung infection, chronic obstructive pulmonary disease (COPD), asthma, and pulmonary fibrosis. This review paper aims to provide an overview of the current research on human NEU1 and respiratory diseases.
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页数：8
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