Mass spectrometry-based proteomic applications in dental implants research

被引：1
|
作者：
Halstenbach, Tim [1 ]
Topitsch, Annika [1 ,2 ,3 ,4 ]
Schilling, Oliver [2 ]
Iglhaut, Gerhard [1 ]
Nelson, Katja [1 ]
Fretwurst, Tobias [1 ,5 ]
机构：
[1] Univ Freiburg, Fac Med, Med Ctr, Dept Oral and Craniomaxillofacial Surg Translat Im, Freiburg, Germany
[2] Univ Freiburg, Inst Surg Pathol, Fac Med, Med Ctr, Freiburg, Germany
[3] Univ Freiburg, Spemann Grad Sch Biol & Med SGBM, Freiburg, Germany
[4] Univ Freiburg, Fac Biol, Freiburg, Germany
[5] Univ Freiburg, Fac Med, Med Ctr, Dept Oral and Craniomaxillofacial Surg Translat Im, Hugstetter Str 55, D-79106 Freiburg, Germany
来源：
PROTEOMICS CLINICAL APPLICATIONS | 2024年 / 18卷 / 03期
关键词：
alveolar bone; dental implants; peri-implant crevicular fluid; peri-implantitis; proteomics; BONE LOSS BIOMARKERS; PERI-IMPLANTITIS; CREVICULAR FLUID; MATRIX METALLOPROTEINASE-8; NATURAL TEETH; GINGIVAL; HEALTH; PERIODONTITIS; EXPRESSION; DISEASE;
D O I：
10.1002/prca.202300019
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Dental implants have been established as successful treatment options for missing teeth with steadily increasing demands. Today, the primary areas of research in dental implantology revolve around osseointegration, soft and hard tissue grafting as well as peri-implantitis diagnostics, prevention, and treatment. This review provides a comprehensive overview of the current literature on the application of MS-based proteomics in dental implant research, highlights how explorative proteomics provided insights into the biology of peri-implant soft and hard tissues and how proteomics facilitated the stratification between healthy and diseased implants, enabling the identification of potential new diagnostic markers. Additionally, this review illuminates technical aspects, and provides recommendations for future study designs based on the current evidence.
引用
收藏
页数：16
相关论文
共 50 条
  • [1] Progress in mass spectrometry-based proteomic research of tumor hypoxia
    Gao, Zhiqi
    Luo, Gang
    Ni, Bing
    ONCOLOGY REPORTS, 2017, 38 (02) : 676 - 684
  • [2] Mass spectrometry-based proteomic quest for diabetes biomarkers
    Shao, Shiying
    Guo, Tiannan
    Aebersold, Ruedi
    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2015, 1854 (06): : 519 - 527
  • [3] Mass spectrometry-based proteomic approach in Juglans Regia
    Aiello, Donatella
    Key Engineering Materials, 2021, 885 : 25 - 31
  • [4] The Warburg Effect and Mass Spectrometry-based Proteomic Analysis
    Zhou, Weidong
    Liotta, Lance A.
    Petricoin, Emanuel F.
    CANCER GENOMICS & PROTEOMICS, 2017, 14 (04) : 211 - 218
  • [5] Mass spectrometry-based metabolomics: applications to biomarker and metabolic pathway research
    Zhang, Aihua
    Sun, Hui
    Yan, Guangli
    Wang, Ping
    Wang, Xijun
    BIOMEDICAL CHROMATOGRAPHY, 2016, 30 (01) : 7 - 12
  • [6] Mass Spectrometry-Based Metabolomic and Proteomic Strategies in Organic Acidemias
    Imperlini, Esther
    Santorelli, Lucia
    Orru, Stefania
    Scolamiero, Emanuela
    Ruoppolo, Margherita
    Caterino, Marianna
    BIOMED RESEARCH INTERNATIONAL, 2016, 2016
  • [7] Mass spectrometry-based phosphoproteomics in clinical applications
    Wu, Xiaofeng
    Liu, Yi-Kai
    Iliuk, Anton B.
    Tao, W. Andy
    TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2023, 163
  • [8] Statistical Design of Quantitative Mass Spectrometry-Based Proteomic Experiments
    Oberg, Ann L.
    Vitek, Olga
    JOURNAL OF PROTEOME RESEARCH, 2009, 8 (05) : 2144 - 2156
  • [9] Mass spectrometry-based proteomic analysis of the DNA damage response
    Stokes, Matthew P.
    Zhu, Yiying
    Farnsworth, Charles L.
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2018, 23 : 597 - 613
  • [10] Mass spectrometry-based proteomic analyses of contact lens deposition
    Green-Church, Kari B.
    Nichols, Jason J.
    MOLECULAR VISION, 2008, 14 (36-37): : 291 - 297
12345