Overlapping Epstein-Barr virus encephalitis and autoimmune glial fibrillary acidic protein astrocytopathy

被引：4

作者：

Zhang, Jin-ru ^{[1
,2
]}

Zhuang, Sheng ^{[1
,2
]}

Xu, Xiao-dong ^{[1
,2
]}

Song, Wen-li ^{[1
,2
]}

Li, Ke-ru ^{[1
,2
]}

Jiang, Yu ^{[1
,2
]}

Cheng, Xiao-yu ^{[1
,2
]}

Shi, Ji-jun ^{[1
,2
]}

Hu, Wei-dong ^{[1
,2
,5
]}

Liu, Chun-feng ^{[1
,2
,3
,4
,5
]}

Zhang, Yan-lin ^{[1
,2
,5
]}

机构：

[1] Soochow Univ, Dept Neurol, Affiliated Hosp 2, Suzhou, Peoples R China

[2] Soochow Univ, Suzhou Clin Res Ctr Neurol Dis, Affiliated Hosp 2, Suzhou, Peoples R China

[3] Soochow Univ, Jiangsu Key Lab Neuropsychiat Dis, Suzhou, Peoples R China

[4] Soochow Univ, Inst Neurosci, Suzhou, Peoples R China

[5] Soochow Univ, Dept Neurol, Affiliated Hosp 2, 1055 Sanxiang Rd, Suzhou 215004, Peoples R China

来源：

JOURNAL OF NEUROIMMUNOLOGY | 2023年 / 382卷

关键词：

Autoimmune glial fibrillary acidic protein astrocytopathy; Epstein-Barr virus encephalitis; Acute disseminated encephalomyelitis;

D O I：

10.1016/j.jneuroim.2023.578174

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We describe three cases of overlapping Epstein-Barr virus (EBV) Encephalitis and Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy (GFAP-A). The three cases all presented with initial symptoms of fever, headache, coma, and posture tremor of the upper limbs, then followed by limb weakness and dysuria. All of the three cases were on ventilators. Case 1 and 2 improved dramatically after intravenous methylprednisoloneand immuno-globulin treatment. However, case 3 presented dyspneic, and died from gastrointestinal hemorrhage. The GFAP-A triggered by EBV intracranial infection could initially masquerade as EBV encephalitis only, and the detection of GFAP antibody is essential for differentiation.

引用

页数：5

共 50 条

[41] A Case of Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy (GFAP) Meningoencephalomyelitis Responsive to Infliximab
Rodriguez, Justin
Romero, Rebecca
NEUROLOGY, 2019, 92 (15)
[42] Failure of IVIG in Steroid-responsive Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy
Chaudhari, Amit
Lam, Chelsea
Pirverdian, Ateena
Lai, Sam
Courtney, Ardith
NEUROLOGY, 2020, 94 (15)
[43] Autoimmune glial fibrillary acidic protein astrocytopathy associated with breast cancer: a case report
Yaguchi, Tomonori
Kimura, Akio
Takekoshi, Akira
Matsuo, Mikiko
Tomita, Hiroyuki
Shimohata, Takayoshi
BMC NEUROLOGY, 2023, 23 (01)
[44] Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy in Children: A Retrospective Analysis of 35 Cases
Fang, Hongjun
Hu, Wenjing
Jiang, Zhi
Yang, Haiyan
Liao, Hongmei
Yang, Liming
Wu, Liwen
FRONTIERS IN IMMUNOLOGY, 2021, 12
[45] Autoimmune glial fibrillary acidic protein astrocytopathy: clinical analysis and review of 15 cases
Wei Lan
Jiming Li
Peiying Ai
Weiliang Luo
Acta Neurologica Belgica, 2023, 123 : 1465 - 1479
[46] Overlapping Autoimmune Syndromes in Patients With Glial Fibrillary Acidic Protein Antibodies
Yang, Xinguang
Xu, Huiming
Ding, Meilin
Huang, Qingmei
Chen, Baikeng
Yang, Huacai
Liu, Tianni
Long, Youming
Gao, Cong
FRONTIERS IN NEUROLOGY, 2018, 9
[47] Autoimmune glial fibrillary acidic protein astrocytopathy associated with breast cancer: a case report
Tomonori Yaguchi
Akio Kimura
Akira Takekoshi
Mikiko Matsuo
Hiroyuki Tomita
Takayoshi Shimohata
BMC Neurology, 23
[48] Excessive daytime sleepiness as a presenting manifestation of autoimmune glial fibrillary acidic protein astrocytopathy
Tang, Mingyang
Huang, Shuo
Guo, Weitong
Zhou, Junfang
Huang, Zhencan
Li, Wanru
Sun, Qingqing
Wang, Zan
FRONTIERS IN IMMUNOLOGY, 2023, 14
[49] A case of autoimmune glial fibrillary acidic protein astrocytopathy presenting with encephalomyelitis and severe peripheral neuropathy
Yuan, Wei
Lv, Wenming
Zhang, Zhenchang
NEUROLOGICAL SCIENCES, 2023, 44 (06) : 2195 - 2197
[50] Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy masquerading as tuberculosis of the central nervous system
Tang, David
Chin, Amanda
Quek, Amy May Lin
NEUROLOGY, 2020, 94 (15)

← 1 2 3 4 5 →