Single-shot OCT and OCT angiography for slab-specific detection of diabetic retinopathy

被引：0

作者：

Liang, Guangru b. ^{[1
,2
]}

Hormel, Tristan t. ^{[1
,2
]}

Wei, Xiang ^{[1
,2
]}

Guo, Yukun ^{[1
,2
]}

Wang, Jie ^{[1
,2
]}

Hwang, Thomas ^{[1
,2
]}

Jia, Yali ^{[1
,2
]}

机构：

[1] Oregon Hlth & Sci Univ, Dept Biomed Engn, 3303 SW Bond Ave, Portland, OR 97239 USA

[2] Oregon Hlth & Sci Univ, Casey Eye Inst, 515 SW Campus Dr, Portland, OR 97239 USA

来源：

BIOMEDICAL OPTICS EXPRESS | 2023年 / 14卷 / 11期

基金：

美国国家卫生研究院;

关键词：

OPTICAL COHERENCE TOMOGRAPHY; CAPILLARY PLEXUSES; PERIPHERAL LESIONS; VISUAL-ACUITY; CHORIOCAPILLARIS; DEGENERATION; VASCULATURE; DISRUPTION; RANGE; LAYER;

D O I：

10.1364/BOE.503476

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

In this study, we present an optical coherence tomographic angiography (OCTA) prototype using a 500 kHz high-speed swept-source laser. This system can generate a 75-degree field of view with a 10.4 mu m lateral resolution with a single acquisition. With this prototype we acquired detailed, wide-field, and plexus-specific images throughout the retina and choroid in eyes with diabetic retinopathy, detecting early retinal neovascularization and locating pathology within specific retinal slabs. Our device could also visualize choroidal flow and identify signs of key biomarkers in diabetic retinopathy.

引用

页码：5682 / 5695

页数：14

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