A novel small molecule induces necroptosis and autophagy in non-homologous recombination deficient ovarian cancer

被引：0
|
作者：
Persenaire, Christianne [1 ]
Babbs, Beatrice [1 ]
Lambert, James [1 ]
Bitler, Benjamin [1 ]
机构：
[1] Univ Colorado, Anschutz Med Ctr, Denver, CO USA
来源：
GYNECOLOGIC ONCOLOGY | 2023年 / 176卷
关键词：
D O I：
10.1016/j.ygyno.2023.06.169
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
1260
引用
收藏
页码：S165 / S165
页数：1
相关论文
共 50 条
  • [21] CXCL10 and CCL5 as feasible biomarkers for immunotherapy of homologous recombination deficient ovarian cancer
    Han, Yue
    Guo, Zhewei
    Jiang, Lijuan
    Li, Xinyue
    Chen, Jiahui
    Ouyang, Ling
    Li, Yan
    Wang, Xiaoying
    AMERICAN JOURNAL OF CANCER RESEARCH, 2023, 13 (05): : 1904 - +
  • [22] Germline and somatic mutations of homologous recombination associated genes in non-serous ovarian cancer
    Sugino, Kentaro
    Yoshihara, Kosuke
    Yamaguchi, Manako
    Yachida, Nozomi
    Mori, Yutaro
    Yamawaki, Kaoru
    Suda, Kazuaki
    Tamura, Ryo
    Ishiguro, Tatsuya
    Adachi, Sosuke
    Isobe, Masanori
    Yamaguchi, Masayuki
    Sekine, Masayuki
    Kashima, Katsunori
    Nakaoka, Hirofumi
    Inoue, Ituro
    Enomoto, Takayuki
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2018, 28 : 121 - 121
  • [23] STL127705 synergize with olaparib in castration-resistant prostate cancer by inhibiting homologous recombination and non-homologous end-joining repair
    Sun, Peng
    Zhao, Wenyang
    Li, Haibin
    Feng, Yigeng
    Chen, Lei
    Cao, Hongwen
    AMERICAN JOURNAL OF CANCER RESEARCH, 2023, 13 (05): : 2030 - +
  • [24] A novel ALDH1A selective inhibitor induces necroptosis in ovarian cancer stem -like cells
    Chefetz-Menaker, Ilana
    Yang, Kun
    Buckanovich, Ron
    CANCER RESEARCH, 2016, 76
  • [25] Non-homologous recombination of deoxyribonucleoside kinases from human and Drosophila melanogaster yields human-like enzymes with novel activities
    Gerth, Monica L.
    Lutz, Stefan
    JOURNAL OF MOLECULAR BIOLOGY, 2007, 370 (04) : 742 - 751
  • [26] In vivo antitumor activity of the PARP inhibitor niraparib (MK-4827) in homologous recombination deficient and proficient ovarian cancer
    Al Hilli, Mariam
    Weroha, S. John
    Becker, Marc
    Hou, Xiaonan
    Harrington, Sean
    McKinstrey, Sarah
    Kalli, Kimberly
    Goodman, Karin
    Wilcoxen, Keith
    Swisher, Elizabeth
    Kaufmann, Scott
    Haluska, Paul
    CLINICAL CANCER RESEARCH, 2013, 19
  • [27] Multiomic analysis of homologous recombination-deficient end-stage high-grade serous ovarian cancer
    Burdett, Nikki L.
    Willis, Madelynne O.
    Alsop, Kathryn
    Hunt, Allison L.
    Pandey, Ahwan
    Hamilton, Phineas T.
    Abulez, Tamara
    Liu, Xuan
    Hoang, Therese
    Craig, Stuart
    Fereday, Sian
    Hendley, Joy
    Garsed, Dale W.
    Milne, Katy
    Kalaria, Shreena
    Marshall, Ashley
    Hood, Brian L.
    Wilson, Katlin N.
    Conrads, Kelly A.
    Pishas, Kathleen, I
    Ananda, Sumitra
    Scott, Clare L.
    Antill, Yoland
    McNally, Orla
    Mileshkin, Linda
    Hamilton, Anne
    Au-Yeung, George
    Devereux, Lisa
    Thorne, Heather
    Bild, Andrea
    Bateman, Nicholas W.
    Maxwell, G. Larry
    Chang, Jeffrey T.
    Conrads, Thomas P. P.
    Nelson, Brad H.
    Bowtell, David D. L.
    Christie, Elizabeth L. L.
    NATURE GENETICS, 2023, 55 (03) : 437 - +
  • [28] Multiomic analysis of homologous recombination-deficient end-stage high-grade serous ovarian cancer
    Nikki L. Burdett
    Madelynne O. Willis
    Kathryn Alsop
    Allison L. Hunt
    Ahwan Pandey
    Phineas T. Hamilton
    Tamara Abulez
    Xuan Liu
    Therese Hoang
    Stuart Craig
    Sian Fereday
    Joy Hendley
    Dale W. Garsed
    Katy Milne
    Shreena Kalaria
    Ashley Marshall
    Brian L. Hood
    Katlin N. Wilson
    Kelly A. Conrads
    Kathleen I. Pishas
    Sumitra Ananda
    Clare L. Scott
    Yoland Antill
    Orla McNally
    Linda Mileshkin
    Anne Hamilton
    George Au-Yeung
    Lisa Devereux
    Heather Thorne
    Andrea Bild
    Nicholas W. Bateman
    G. Larry Maxwell
    Jeffrey T. Chang
    Thomas P. Conrads
    Brad H. Nelson
    David D. L. Bowtell
    Elizabeth L. Christie
    Nature Genetics, 2023, 55 : 437 - 450
  • [29] Genomic characteristics underlying homologous recombination deficient-negative scores in ovarian high grade serous cancer tumors
    Fotopoulou, Christina
    Lorentzen, Marc
    Christie, Elizabeth
    Burdett, Nikki
    Pandey, Ahwan
    Nixon, Katherine
    Ploski, Jennifer
    Varghese, Shriya
    Chiu, Selina
    Dickie, Catriona
    Clark, James
    Krell, Jonathan
    Cunnea, Paula
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2024, 34 (SUPPL_3) : A210 - A210
  • [30] Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors
    Luo, Yikai
    Xia, Yu
    Liu, Dan
    Li, Xiong
    Li, Huayi
    Liu, Jiahao
    Zhou, Dongchen
    Dong, Yu
    Li, Xin
    Qian, Yiyu
    Xu, Cheng
    Tao, Kangjia
    Li, Guannan
    Pan, Wen
    Zhong, Qing
    Liu, Xingzhe
    Xu, Sen
    Wang, Zhi
    Liu, Ronghua
    Zhang, Wei
    Shan, Wanying
    Fang, Tian
    Wang, Siyuan
    Peng, Zikun
    Jin, Ping
    Jin, Ning
    Shi, Shennan
    Chen, Yuxin
    Wang, Mengjie
    Jiao, Xiaofei
    Luo, Mengshi
    Gong, Wenjian
    Wang, Ya
    Yao, Yue
    Zhao, Yi
    Huang, Xinlin
    Ji, Xuwo
    He, Zhaoren
    Zhao, Guangnian
    Liu, Rong
    Wu, Mingfu
    Chen, Gang
    Hong, Li
    Ma, Ding
    Fang, Yong
    Liang, Han
    Gao, Qinglei
    CELL, 2024, 187 (18) : 4905 - 4925
12345