Previous SARS-CoV-2 Infection Is Not Associated With Increased Celiac Disease Autoimmunity in Children and Adolescents

被引：1

作者：

Corrado, Michelle M. ^{[1
]}

Jia, Xiaofan ^{[2
]}

Rasmussen, Cristy Geno ^{[2
]}

Pyle, Laura ^{[2
]}

Yu, Liping ^{[2
]}

Liu, Edwin ^{[1
]}

Stahl, Marisa ^{[1
]}

Rewers, Marian J. ^{[2
]}

机构：

[1] Univ Colorado, Digest Hlth Inst, Childrens Hosp Colorado, Aurora, CO 80045 USA

[2] Univ Colorado, Barbara Davis Ctr Diabet, Aurora, CO USA

来源：

AMERICAN JOURNAL OF GASTROENTEROLOGY | 2023年 / 118卷 / 09期

关键词：

celiac disease; SARS-CoV-2; COVID-19; screening;

D O I：

10.14309/ajg.0000000000002317

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

INTRODUCTION:Recent reports suggest severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections may increase the risk of celiac disease autoimmunity. This study aims to evaluate potential associations between coronavirus disease 2019 infection and tissue transglutaminase autoantibodies (TGA) immunoglobulin A.METHODS:From 2020 to 2021, cross-sectional screening for SARS-CoV-2 antibodies and TGA was offered to 4,717 children in Colorado through the Autoimmunity Screening for Kids study. Multivariable logistic regression assessed association between previous SARS-CoV-2 infection and TGA positivity.RESULTS:Previous SARS-CoV-2 infection was not associated with TGA positivity (odds ratio 1.02, 95% confidence interval 0.63-1.59; P = 0.95).DISCUSSION:In this large-scale analysis, previous SARS-CoV-2 infection was not associated with celiac disease autoimmunity in Colorado children.

引用

页码：1698 / 1700

页数：3

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