A comprehensive review on transdermal patches as an efficient approach for the delivery of drug

被引：2

作者：

Ashfaq, Ansa ^{[1
]}

Riaz, Tehseen ^{[1
]}

Waqar, Muhammad Ahsan ^{[2
]}

Zaman, Muhammad ^{[1
]}

Majeed, Imtiaz ^{[1
]}

机构：

[1] Univ Cent Punjab, Fac Pharmaceut Sci, Lahore, Pakistan

[2] Lahore Univ Biol & Appl Sci, Fac Pharmaceut Sci, Dept Pharmaceut, Lahore, Pakistan

来源：

POLYMER-PLASTICS TECHNOLOGY AND MATERIALS | 2024年 / 63卷 / 08期

关键词：

Characterization; drug hydrolysis; skin irritation study; transdermal drug delivery system; transdermal patch; IN-VITRO EVALUATION; CHEMICAL PENETRATION ENHANCERS; PRESSURE-SENSITIVE ADHESIVES; MICRONEEDLE PATCH; PHARMACOKINETIC PROPERTIES; ALZHEIMERS-DISEASE; NITRIC-OXIDE; SYSTEM; FORMULATION; ESTRADIOL;

D O I：

10.1080/25740881.2024.2317408

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

In past years, various studies have considered transdermal drug delivery system for improving patient compliance. One approach to deliver drug via transdermal route is transdermal patch. These patches include single-layer drug in adhesive patches and micro reservoir transdermal patch & matrix system. Acrylic-acid, hydroxypropyl methylcellulose (HPMC) and polyethylene glycol are commonly used polymers for manufacturing of transdermal patches. Characterization of patches includes patch thickness, weight uniformity, irritation studies, in-vitro drug release and permeation studies. This review summarizes various polymers, types of transdermal patches and evaluation of transdermal patches based on up-to-date data extracted from reputed journals and official websites.

引用

页码：1045 / 1069

页数：25

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