A NOVEL APPROACH FOR TRANSDERMAL DRUG DELIVERY SYSTEM (PATCH) - A REVIEW

Transdermal drug delivery system are topically applied medication which is used to deliver the specific dose of drug direct entry into systemic circulation after passing through the skin barrier, and it avoid first pass effect. Transdermal patches deliver the drug for systemic effect at a predetermined and control rate through diffusion process. Transdermal drug technology specialists are continuing to search for new methods that can effectively and painlessly deliver large molecule in therapeutic quantities to overcome the difficulties associated with oral route, like poor bioavailability, first pass metabolism and sometime responsible for rapid blood level. Dermal drug delivery is the dosage form that can transport the drug through viable epidermis and or dermal tissue of the skin for local therapeutic effect. While an important function transport the drug intosystemic blood circulation at controlled rate. Purpose of write the review article provide the overview of transdermal drug delivery like drug delivery route across human skin, permeation enhancer used in TDDS, components used in TDDS, how many type of transdermal patch, advantage and disadvantage and its methods of evaluation.