A novel HIF2A mutation causes dyslipidemia and promotes hepatic lipid accumulation

被引：0
|
作者：
Gao, Feiqiong [1 ]
Yao, Qigu [1 ]
Zhu, Jiaqi [1 ]
Chen, Wenyi [1 ]
Feng, Xudong [1 ]
Feng, Bing [1 ]
Yu, Jiong [1 ]
Cao, Hongcui [1 ]
机构：
[1] Zhejiang Univ, Affiliated Hosp 1, Sch Med, Hangzhou, Peoples R China
来源：
JOURNAL OF HEPATOLOGY | 2023年 / 78卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
WED-429
引用
收藏
页码：S753 / S753
页数：1
相关论文
共 50 条
  • [31] PDGFRβ + cell HIF2α is dispensable for white adipose tissue metabolic remodeling and hepatic lipid accumulation in obese mice
    Yao, Tao
    Wei, Danni
    Tian, Xin
    Zhao, Lin
    Wan, Qiangyou
    Zhang, Xiaoli
    Cai, Juan
    Li, Siqi
    Diao, Bowen
    Feng, Suihan
    Shan, Bo
    Shao, Mengle
    Wu, Ying
    LIPIDS IN HEALTH AND DISEASE, 2024, 23 (01)
  • [32] Three Novel EPAS1/HIF2A Somatic and Germline mutations Associated with Polycythemia and Pheochromocytoma/Paraganglioma
    Lorenzo, Felipe R.
    Zhuang, Zhengping
    Yang, Chunzhang
    Fui, Mark Ng Tang
    Vankayalapati, Hariprasad
    Pacak, Karel
    Prchal, Josef T.
    BLOOD, 2012, 120 (21)
  • [33] Exosome secretion promotes proliferation of African American prostate cancer cells under hypoxia: Role of HIF2A and RAB signaling
    Panigrahi, Gatikrushna
    Peak, Taylor C.
    Patterson, Sierra L.
    Kasica, Nicole
    Singh, Ravi
    Hemal, Ashok
    Deep, Gagan
    CANCER RESEARCH, 2017, 77
  • [34] EHD1 promotes breast cancer metastasis through upregulating HIF2a expression via activating mTOR pathway
    Gao, Xiaoqian
    Li, Juan
    Feng, Xuefei
    Xie, Yuchen
    Zhang, Juan
    Liu, Jie
    Wang, Bo
    Liu, Peijun
    FASEB JOURNAL, 2024, 38 (21):
  • [35] Mutation in the promoter region of the hepatic lipase gene correlates with dyslipidemia in type 2 diabetes
    Mattu, RK
    Needham, EW
    Trevelyan, J
    Richter, DJ
    Adiseshiah, MA
    Lencioni, M
    Gieowarsingh, S
    Betteridge, DJ
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2002, 39 (05) : 226A - 226A
  • [36] Xanthine oxidase promotes hepatic lipid accumulation through high fat absorption by the small intestine
    Liu, Lin
    Zhang, Yuntao
    Wang, Xuanyang
    Meng, Hongxue
    He, Yan
    Xu, Xiaoqing
    Xu, Huan
    Wei, Chunbo
    Yan, Xuemin
    Tao, Xinmiao
    Dang, Keke
    Ma, Pingnan
    Guo, Xiaoyu
    Yang, Sen
    Wang, Jiemei
    Li, Ying
    JHEP REPORTS, 2024, 6 (08)
  • [37] Dysregulated Autophagy in Hepatocytes Promotes Bisphenol A-Induced Hepatic Lipid Accumulation in Male Mice
    Yang, Shumin
    Zhang, Aipin
    Li, Ting
    Gao, Rufei
    Peng, Chuan
    Liu, Lulu
    Cheng, Qingfeng
    Mei, Mei
    Song, Ying
    Xiang, Xiaojiao
    Wu, Chaodong
    Xiao, Xiaoqiu
    Li, Qifu
    ENDOCRINOLOGY, 2017, 158 (09) : 2799 - 2812
  • [38] A Novel Mechanism for Hepatic Lipid Accumulation: A Physiological Role for Hepatic PPARγ-fsp27 Signal
    Matsusue, Kimihiko
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2012, 132 (07): : 823 - 829
  • [39] Novel HIF2A mutations disrupting oxygen sensing lead to a new syndrome of multiple paragangliomas and somatostatinomas associated with polycythemia
    Yang, Chunzhang
    Pacak, Karel
    Zhuang, Zhengping
    CANCER RESEARCH, 2014, 74 (23)
  • [40] Life Long High Fat Diet Causes Hepatic Lipid Accumulation by Programming Lipid Synthesis Genes in Liver of Male Rat
    Jung, Paul Mark
    Zhou, Dan
    Moody, Laura
    Kriska, Adam
    Chen, Hong
    Pan, Yuan-Xiang
    FASEB JOURNAL, 2016, 30
12345