Surgical radioguidance with beta-emitting radionuclides; challenges and possibilities: A position paper by the EANM

被引：5

作者：

Costa, Pedro Fragoso ^{[1
]}

Shi, Kuangyu ^{[2
,3
]}

Holm, Soren ^{[4
]}

Vidal-Sicart, Sergi ^{[5
]}

Kracmerova, Tereza ^{[6
]}

Tosi, Giovanni ^{[7
]}

Grimm, Jan ^{[8
,9
]}

Visvikis, Dimitris ^{[10
]}

Knapp, Wolfram H. ^{[11
]}

Gnanasegaran, Gopinath ^{[12
,13
]}

van Leeuwen, Fijs W. B. ^{[14
]}

机构：

[1] Univ Duisburg Essen, Univ Hosp Essen, West German Canc Ctr WTZ, Dept Nucl Med, Essen, Germany

[2] Bern Univ Hosp, Univ Bern, Dept Nucl Med, Inselspital, Bern, Switzerland

[3] Tech Univ Munich, Inst Informat I16, Comp Aided Med Procedures & Augmented Real, Munich, Germany

[4] Univ Hosp Copenhagen, Dept Clin Physiol Nucl Med & PET, Rigshosp, Copenhagen, Denmark

[5] Hosp Clin Barcelona, Nucl Med Dept, Barcelona, Spain

[6] Motol Univ Hosp, Dept Med Phys, Prague, Czech Republic

[7] Osped U Parini, Dept Med Phys, Aosta, Italy

[8] Mem Sloan Kettering Canc Ctr, Mol Pharmacol Program, New York, NY USA

[9] Mem Sloan Kettering Canc Ctr, Dept Radiol, New York, NY USA

[10] Univ Brest, UMR 1101, LaTIM, INSERM, Brest, France

[11] Hannover Med Sch, Dept Nucl Med, Hannover, Germany

[12] Univ Coll London Hosp, Inst Nucl Med, Tower 5,235 Euston Rd, London NW1 2BU, England

[13] Royal Free London NHS Fdn Trust Hosp, London, England

[14] Leiden Univ, Med Ctr, Dept Radiol, Intervent Mol Imaging Lab, Leiden, Netherlands

来源：

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING | 2024年 / 51卷 / 10期

关键词：

Beta emitting Radionuclides; Radioguidance; Radiotracers; Image guided surgery; Radiation exposure; RADIO-GUIDED SURGERY; SENTINEL NODE BIOPSY; PIXEL READOUT CHIP; IN GAMMA-PROBE; HAND-HELD; IMAGING PROBE; LYMPH-NODES; POSITRON; LOCALIZATION; CANCER;

D O I：

10.1007/s00259-023-06560-2

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Radioguidance that makes use of beta-emitting radionuclides is gaining in popularity and could have potential to strengthen the range of existing radioguidance techniques. While there is a strong tendency to develop new PET radiotracers, due to favorable imaging characteristics and the success of theranostics research, there are practical challenges that need to be overcome when considering use of beta-emitters for surgical radioguidance. In this position paper, the EANM identifies the possibilities and challenges that relate to the successful implementation of beta-emitters in surgical guidance, covering aspects related to instrumentation, radiation protection, and modes of implementation.

引用

页码：2903 / 2921

页数：19

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