Enhanced suppression of otoacoustic emissions by contralateral stimulation in Parkinson's disease

被引：0

作者：

Moleti, Arturo ^{[1
]}

Minniti, Triestino ^{[1
]}

Viziano, Andrea ^{[2
]}

Stefani, Alessandro ^{[3
]}

Cerroni, Rocco ^{[3
]}

Garasto, Elena ^{[3
]}

Pierantozzi, Mariangela ^{[3
]}

Sisto, Renata ^{[4
]}

机构：

[1] Univ Roma Tor Vergata, Dept Phys, I-00133 Tor Vergata, Italy

[2] Univ Roma Tor Vergata, Dept Clin Sci & Translat Med, I-00133 Rome, Italy

[3] Univ Roma Tor Vergata, Parkinsons Dis Ctr, Dept Syst Med, I-00133 Rome, Italy

[4] Ist Nazl Assicuraz Contro Infortuni Lavoro, Dept Occupat & Environm Med, Epidemiol & Hyg, I-00100 Rome, Italy

来源：

JASA EXPRESS LETTERS | 2023年 / 3卷 / 10期

关键词：

D O I：

10.1121/10.0021187

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

Dopamine depletion affects several aspects of hearing function. Previous work [Wu, Yi, Manca, Javaid, Lauer, and Glowatzki, eLife 9, e52419 (2020)] demonstrated the role of dopamine in reducing the firing rates of inner ear cells, which is thought to decrease synaptic excitotoxicity. Thus, a lack of dopamine could indirectly increase acoustic stimulation of medial olivocochlear efferents. To investigate that, here we studied contralateral suppression of distortion product otoacoustic emissions in a population of Parkinsonian patients, compared to an age-matched control group, both audiometrically tested. To rule out activation of the acoustic reflex, middle ear impedance was monitored during testing. The results show significantly stronger contralateral suppression in the patient group.

引用

页数：6

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