Endothelin signalling drives dermal sheath smooth muscle contraction for hair follicle regression

被引：0

作者：

Rendl, Michael ^{[1
]}

Sunkara, Raghava ^{[1
]}

机构：

[1] Icahn Sch Med Mt Sinai, New York, NY 10029 USA

来源：

NATURE CELL BIOLOGY | 2023年 / 25卷 / 02期

关键词：

D O I：

10.1038/s41556-022-01077-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Contraction of the hair follicle-lining dermal sheath smooth muscle generates the forces necessary for the tissue remodelling that takes place during the regression phase of the hair growth cycle. This study reveals that endothelin signalling - from epithelial progenitors at the follicle bottleneck region to its neighbouring dermal sheath - is the main contraction-activating pathway.

引用

页码：220 / 221

页数：2

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