Candida biofilm formation and recurrent vulvovaginal candidiasis

被引:0
|
作者
Sun, Yao [1 ,2 ]
Kostoulias, Xenia [1 ,3 ,4 ]
Qu, Yue [1 ,3 ,4 ]
机构
[1] Monash Univ, Biomed Discovery Inst, Fac Med Nursing & Hlth Sci, Dept Microbiol, Clayton, Vic 3800, Australia
[2] Wenzhou Med Univ, Affiliated Hosp 1, Dept Lab Med, Wenzhou 325000, Zhejiang, Peoples R China
[3] Monash Univ, Alfred Hosp, Dept Infect Dis, Melbourne, Vic 3004, Australia
[4] Monash Univ, Cent Clin Sch, Melbourne, Vic 3004, Australia
关键词
antifungal resistance; biofilm formation; Candida species; pathogenesis; persistence; recurrence; vulvovaginal candidiasis; GENE-EXPRESSION; ALBICANS; EPIDEMIOLOGY; RESISTANCE; VIRULENCE; VAGINITIS; DEVICES; FAMILY;
D O I
10.1071/MA23026
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Recurrent vulvovaginal candidiasis (RVVC), a recalcitrant Candida infection of the lower female reproductive tract, is a difficult-to-treat medical condition affecting the morbidity of many otherwise healthy women. Cumulative experimental evidence supports the involvement of biofilm formation of Candida in the pathogenesis of RVVC and its treatment failure. In this review, we will discuss important insights into the roles of Candida biofilms in RVVC.
引用
收藏
页码:92 / 95
页数:4
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