Gastric Carcinoma With Sebaceous Differentiation and SALL4 Expression

被引：0
|
作者：
Nakanishi, Takaaki [1 ]
Akita, Masayuki [2 ]
Ichikawa, Chihiro [1 ]
Kaneda, Kunihiko [2 ]
Tamura, Isamu [3 ]
Kawata, Yumiko [4 ]
Takahashi, Masayuki [5 ]
Imai, Yukihiro [1 ]
机构：
[1] Kakogawa Cent City Hosp, Dept Surg Pathol, Kakogawa, Japan
[2] Kakogawa Cent City Hosp, Dept Surg, Kakogawa, Japan
[3] Hyogo Prefectural Kakogawa Med Ctr, Div Gastroenterol, Kakogawa, Japan
[4] Kakogawa Cent City Hosp, Dept Dermatol, Kakogawa, Japan
[5] Kakogawa Cent City Hosp, Dept Otorhinolaryngol, Kakogawa, Japan
来源：
ACG CASE REPORTS JOURNAL | 2023年 / 10卷 / 05期
关键词：
stomach; AFP-producing adenocarcinoma; sebaceous carcinoma; SALL4;
D O I：
10.14309/crj.0000000000001061
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
A sebaceous carcinoma is rarely seen in extracutaneous sites. We present a 75-year-old man who was admitted with epigastralgia and melena. Endoscopic examination revealed an ulcer on the posterior wall of the gastric antrum, and distal gastrectomy was performed. Histopathological examination revealed thin to thick trabeculae of polygonal cells with scattered foci of foamy cells, whereas Sudan 3 staining showed lipid vacuoles. Immunohistochemistry was positive for both p40 and SALL4. After considering these findings, we suggest sebaceous differentiation as the diagnosis. To the best of our knowledge, this is the first case of gastric carcinoma with sebaceous differentiation.
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页数：4
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